Méthylènedioxyphénmétrazine

MDPM is an extremely novel substance with virtually no human pharmacological data. It acts as a strong CYP2D6 inhibitor and moderate CYP3A4/CYP1A2 inhibitor, creating significant drug-drug interaction risks when combined with medications or substances metabolized by these enzymes. Often appears as a synthetic impurity in MDMA manufacture. Confirm identity with spectroscopy before use. Use professional reagent testing, employ allergy tests, and practice incremental dosing.

Also known as: Mdpm, 3-mdpm, 3,4-mdpm

Classification

Chemical: Phenylmorpholine
Psychoactive: Stimulant
Tag: Phenmetrazine
Tag: Research-Chemical

Effects

Stimulation
Increased Heart Rate
Teeth Grinding
Pupil Dilation
Insomnia
Jaw Tension
Increased Motivation
Focus Enhancement
Euphoria
Empathy
Anxiety
Empathy Enhancement
Appetite Suppression
Light Sensitivity
Increased Libido
Increased Music Appreciation
Tinnitus
Dehydration

Routes of Administration

Oral

Dosage

Threshold: 50-75 mg
Light: 75-150 mg
Common: 150-250 mg
Strong: 250-400 mg
Heavy: 400+ mg

Duration

Onset: 0.25-0.67 h
Peak: 1-3 h
Offset: 2-4 h
After Effects: 6-14 h
Total Duration: 4-7 h

Insufflated

Dosage

Threshold: 20-40 mg
Light: 40-75 mg
Common: 75-125 mg
Strong: 125-200 mg
Heavy: 200+ mg

Duration

Onset: 0.08-0.17 h
Peak: 0.5-1.5 h
Offset: 1.5-3 h
After Effects: 2-6 h
Total Duration: 2-4 h

Harm Reduction

Check interactions before mixing substances, pay attention to dose spacing and hydration, and treat all dosage guidance as approximate rather than guaranteed safe.

Sources

Substance data is aggregated from the following public harm-reduction and reference sources.

dose.wiki

Links

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