Nitrous oxide can cause severe and potentially irreversible vitamin B12 depletion with frequent or chronic use, leading to serious neurological damage including numbness, tingling, and motor control loss. Always supplement with vitamin B12 when using this substance. Never inhale directly from cartridges or tanks due to extreme cold temperature (-40C) which can cause frostbite to lips, throat, and lungs, and high pressure which can rupture lung tissue. Always release gas into a balloon first to warm and depressurize. Ensure adequate oxygen intake between inhalations to prevent hypoxia and brain damage.
Also known as: Nos, N2o, N20, Nangs, Nitro, Gaz hilarant
Classification
Psychoactive: Dissociative
Tag: Anesthetic
Tag: Common
Tag: Habit-Forming
Tag: Hallucinogen
Tag: Inhalant
Tag: Nitrogen oxide
Effects
Physical Euphoria
Sedation
Reduction Of External Stimuli
Analgesia
Buzzing Sensation In Nerve
Nausea
Cognitive Euphoria
Ego Death
Laughter Fits
Motor Control Loss
Dissociation
Time Distortion
Auditory Distortion
Visual Geometry
Tactile Suppression
Sound Distortion
Minor To Strong Hallucinations
Acuity Suppression
Routes of Administration
Inhaled
Dosage
Threshold: 4 g
Light: 4-8 g (0.5-1 cartridge)
Common: 8-16 g (1-2 cartridges)
Strong: 16-40 g (2-5 cartridges)
Heavy: 40 g (5 cartridges)
Duration
Onset: 0-0 h
Peak: 0-0.01 h
Offset: 0.02-0.08 h
After Effects: 0.25-0.5 h
Harm Reduction
Check interactions before mixing substances, pay attention to dose spacing and hydration, and treat all dosage guidance as approximate rather than guaranteed safe.
Sources
Substance data is aggregated from the following public harm-reduction and reference sources.
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Nitrous Oxide - Guide des substances DrugsPRO
Nitrous Oxide: Nitrous oxide can cause severe and potentially irreversible vitamin B12 depletion with frequent or chronic use, leading to serious neurological damage including numbness, tingling, and motor control loss. Always supplement with vitamin B12 when using this substance. Never inhale direc