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Pipradrol

Pipradrol is a central nervous system stimulant of the diphenylmethane class. Originally developed in the 1940s, it saw clinical use in the treatment of depression, fatigue, dementia, and ADHD, among other conditions. Despite demonstrating therapeutic efficacy across a range of psychiatric applications, its significant abuse potential and associated adverse effects led to its withdrawal from medical use and subsequent international scheduling beginning in the 1970s.

Pipradrol molecular structure
Pipradrol molecular structure diagram from the DrugsPRO substance library.

Also known as: Meratran, Alertonic

Classification

  • Psychoactive: Stimulant
  • Tag: Pipradrol homologue

Effects

  • Stimulation
  • Nausea
  • Seizure
  • Restlessness
  • Increased Heart Rate
  • Loss Of Appetite
  • Euphoria
  • Anxiety
  • Wakefulness
  • Thought Acceleration
  • Increased Focus
  • Irritability
  • Light Sensitivity
  • Appetite Suppression
  • Increased Libido
  • Auditory Hallucination
  • External Hallucination
  • Increased Sexuality

Routes of Administration

Insufflated

Dosage

  • Heavy: 60 mg
  • Strong: 60 mg
  • Light: Not established (avoid) mg
  • Common: Not established (avoid) mg
  • Threshold: Not established (avoid) mg

Duration

  • Onset: 0.33 h
  • Comeup: 0.67 h
  • Peak: 1 h
  • Offset: 2 h

Oral

Dosage

  • Light: 0.5 mg
  • Strong: 5-10 mg
  • Heavy: Above 10 mg
  • Common: 2-4 mg
  • Threshold: 0.5 mg

Duration

  • Onset: 0.25-1 h
  • Peak: 1-3 h
  • Offset: 4-8 h
  • After Effects: 6-24 h
  • Total Duration: 6-12 h

Harm Reduction

Check interactions before mixing substances, pay attention to dose spacing and hydration, and treat all dosage guidance as approximate rather than guaranteed safe.

Sources

Substance data is aggregated from the following public harm-reduction and reference sources.

Links

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Pipradrol - Guide des substances DrugsPRO

Pipradrol: Pipradrol is a central nervous system stimulant of the diphenylmethane class. Originally developed in the 1940s, it saw clinical use in the treatment of depression, fatigue, dementia, and ADHD, among other conditions. Despite demonstrating therapeutic efficacy across a range of psychiatri

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