3C-E is the α-methyl homologue of escaline and sits pharmacologically between the 2C-series and the longer-acting DOx family. Street material has ranged from fluffy white powder to off-white crystals – always verify identity with Marquis/Mecke reagents and, ideally, FT-IR or GC-MS. Most users describe a 'bimodal' experience: colourful mescaline-like visuals and empathic warmth alongside noticeable peripheral stimulation (jaw tension, sweating, mild hypertension). Body-load is highly dose-dependent; doses ≥50 mg frequently produce tachycardia, nausea or vascular tightness. Start low, dose once, stay hydrated, and allocate 12-16 hours without responsibilities.
Also known as: 3c-escaline, Alpha‑methyl escaline
Classification
Chemical: Amphetamine
Chemical: Phenethylamine
Psychoactive: Psychedelic
Psychoactive: Stimulant
Tag: Hallucinogen
Tag: Research-Chemical
Tag: Substituted amphetamine
Effects
Stimulation
Physical Euphoria
Nausea
Increased Blood Pressure
Increased Heart Rate
Increased Perspiration
Depth Perception Distortions
Perspective Distortion
Conceptual Thinking
Thought Acceleration
Thought Connectivity
Analysis Enhancement
Spontaneous Physical Sensations
Bodily Control Enhancement
Tactile Enhancement
Appetite Suppression
Dehydration
Color Enhancement
Routes of Administration
Oral
Dosage
Threshold: 15-20 mg
Light: 20-35 mg
Common: 35-50 mg
Strong: 50-70 mg
Heavy: >70 mg
Duration
Onset: 0.5-1.5 h
Comeup: 0.5-1.5 h
Peak: 4-8 h
Offset: 3-6 h
After Effects: 2-16 h
Total Duration: 8-14 h
Insufflated
Dosage
Threshold: 5-8 mg
Light: 8-15 mg
Common: 15-25 mg
Strong: 25-35 mg
Heavy: >35 mg
Duration
Onset: 0.05-0.3 h
Comeup: 0.33-1 h
Peak: 4-7 h
Offset: 2-5 h
After Effects: 2-12 h
Total Duration: 6-12 h
Harm Reduction
Check interactions before mixing substances, pay attention to dose spacing and hydration, and treat all dosage guidance as approximate rather than guaranteed safe.
Sources
Substance data is aggregated from the following public harm-reduction and reference sources.
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3C-E - Treoir substaint DrugsPRO
3C-E: 3C-E is the α-methyl homologue of escaline and sits pharmacologically between the 2C-series and the longer-acting DOx family. Street material has ranged from fluffy white powder to off-white crystals – always verify identity with Marquis/Mecke reagents and, ideally, FT-IR or GC-MS. Most users
