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4-MeO-MiPT

4-MeO-MiPT (4-methoxy-N-methyl-N-isopropyltryptamine) is a rare synthetic psychedelic first reported by Alexander Shulgin (TiHKAL #39). User reports describe a relatively gentle, tactile, and mood-enhancing experience with mild visual effects and a shorter duration than related tryptamines. Recent pharmacological research reveals 4-MeO-MiPT exhibits potent serotonin reuptake inhibition (SSRI activity, IC50 = 57 nM) alongside 5-HT2A and 5-HT1A receptor agonism, which may account for its atypical psychedelic profile characterized by reduced classical psychedelic effects compared to 4-HO-MiPT and 4-AcO-MiPT. Body load is usually mild (slight jaw tension, pupil dilation, occasional nausea). Potency appears 1.5-2x weaker than 5-MeO-MiPT but batches on the grey market vary; test a low allergy dose (<1 mg).

Classification

  • Chemical: Tryptamine
  • Psychoactive: Psychedelic
  • Tag: Hallucinogen
  • Tag: Research-Chemical
  • Tag: Tentative

Effects

  • Body High
  • Mild Stimulation
  • Restlessness
  • Jaw Tension
  • Bruxism
  • Sweating
  • Mood Lift
  • Euphoria
  • Enhanced Sociability
  • Empathy
  • Increased Talkativeness
  • Time Dilation
  • Tactile Enhancement
  • Visual Patterning
  • Tracers
  • Color Saturation
  • Auditory Enhancement
  • Brightened Color

Routes of Administration

Oral

Dosage

  • Threshold: 4 mg
  • Light: 4-8 mg
  • Common: 10-20 mg
  • Strong: 18-28 mg
  • Heavy: 28+ mg

Duration

  • Onset: 0.25-0.75 h
  • Comeup: 0.5-1 h
  • Peak: 1-2 h
  • Offset: 1-2 h
  • After Effects: 0.5-3 h
  • Total Duration: 3-6 h

Insufflated

Dosage

  • Threshold: 2 mg
  • Light: 2-4 mg
  • Common: 4-8 mg
  • Strong: 8-12 mg
  • Heavy: 12+ mg

Duration

  • Onset: 0.083-0.25 h
  • Comeup: 0.25-0.5 h
  • Peak: 0.5-1.5 h
  • Offset: 1-2 h
  • After Effects: 0.5-2 h
  • Total Duration: 2.5-5 h

Harm Reduction

Check interactions before mixing substances, pay attention to dose spacing and hydration, and treat all dosage guidance as approximate rather than guaranteed safe.

Sources

Substance data is aggregated from the following public harm-reduction and reference sources.

Links

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4-MeO-MiPT - Treoir substaint DrugsPRO

4-MeO-MiPT: 4-MeO-MiPT (4-methoxy-N-methyl-N-isopropyltryptamine) is a rare synthetic psychedelic first reported by Alexander Shulgin (TiHKAL #39). User reports describe a relatively gentle, tactile, and mood-enhancing experience with mild visual effects and a shorter duration than related tryptamin

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