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AM-2201

AM-2201 is an extremely potent full agonist at CB1/CB2 receptors (~4–10× potency of JWH-018). Milligram-accurate weighing (0.000 mg resolution) and volumetric dilution are strongly recommended; eyeballing plant material almost always leads to overdose. Acute toxicity can include severe anxiety, hypertension, tachyarrhythmia, hyperemesis, and generalized tonic–clonic seizures. Fatalities have been associated with polydrug use and high ambient temperatures (heat stroke). Users should have a sober sitter and avoid driving for several hours after use.

Also known as: NA-5F-PIMO

Classification

  • Chemical: Cannabinoid
  • Chemical: Synthetic cannabinoid
  • Tag: Habit-Forming
  • Tag: Hallucinogen
  • Tag: Research-Chemical
  • Tag: Sedative
  • Tag: Tentative

Effects

  • Powerful Body High
  • Sedation
  • Tachycardia
  • Dry Mouth
  • Profuse Sweating
  • Nausea Vomiting
  • Rapid Euphoria
  • Altered Time Perception
  • Enhanced Music Appreciation
  • Shortterm Memory Suppression
  • Mental Fog
  • Anxiety Panic
  • Visual Distortion At High Dose
  • Stimulus Control Loss
  • Increased Music Appreciation
  • Open Eye Visuals
  • Visual Distortion
  • Auditory Hallucination

Routes of Administration

Vaporized

Dosage

  • Threshold: 0.2 mg
  • Light: 250 – 500 µg
  • Common: 500 – 1 000 µg
  • Strong: 1 – 2 mg
  • Heavy: 500 mg

Duration

  • Onset: 0.02-0.05 h
  • Peak: 0.08-0.25 h
  • Offset: 0.33-1 h
  • After Effects: 0.5-2 h
  • Total Duration: 0.5-1.5 h

Smoked

Dosage

  • Threshold: 0.2 mg
  • Light: 250 – 500 µg
  • Common: 500 – 1 000 µg
  • Strong: 1 – 2 mg
  • Heavy: 500 mg

Duration

  • Onset: 0.02-0.05 h
  • Peak: 0.08-0.25 h
  • Offset: 0.33-1 h
  • After Effects: 0.5-2 h

Oral

Dosage

  • Threshold: 0.5 mg
  • Light: 0.5 – 1 mg
  • Common: 1 – 2 mg
  • Strong: 2 – 3 mg
  • Heavy: 3+ mg

Duration

  • Onset: 0.25-0.5 h
  • Peak: 0.75-1.5 h
  • Offset: 0.33-1 h
  • After Effects: 1-3 h
  • Total Duration: 1-3 h

Vapourized

Dosage

  • Common: 500-1000 ug
  • Light: 250-500 ug
  • Strong: 1-2 mg

Duration

No data available for this section yet.

Harm Reduction

Check interactions before mixing substances, pay attention to dose spacing and hydration, and treat all dosage guidance as approximate rather than guaranteed safe.

Sources

Substance data is aggregated from the following public harm-reduction and reference sources.

Links

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AM-2201 - Treoir substaint DrugsPRO

AM-2201: AM-2201 is an extremely potent full agonist at CB1/CB2 receptors (~4–10× potency of JWH-018). Milligram-accurate weighing (0.000 mg resolution) and volumetric dilution are strongly recommended; eyeballing plant material almost always leads to overdose. Acute toxicity can include severe anxi

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