Dexmethylphenidate is the more pharmacologically active enantiomer of methylphenidate, classified as a central nervous system stimulant and norepinephrine-dopamine reuptake inhibitor. Approved for medical use in the United States in 2001 and sold under the brand name Focalin, it is primarily prescribed for the treatment of ADHD. It is approximately twice as potent as racemic methylphenidate and is reported to produce cleaner stimulant effects with fewer side effects. It is considered habit-forming.
Dexmethylphenidate molecular structure diagram from the DrugsPRO substance library.
Also known as: Focalin xr, Dextromethylphenidate, Dexmethylphenidate er, Dexmethylphenidate hcl er, Dexmethylphenidate extended-release
Classification
Chemical: Medicine
Chemical: Phenidate
Psychoactive: Stimulant
Tag: Common
Tag: Habit-Forming
Effects
Increased Heart Rate
Increased Blood Pressure
Stimulation
Restlessness
Dry Mouth
Nausea
Anxiety
Irritability
Euphoria
Focus Enhancement
Wakefulness
Psychosis
Appetite Suppression
External Hallucination
Visual Acuity Suppression
Light Sensitivity
Dehydration
Increased Music Appreciation
Routes of Administration
Oral
Dosage
Heavy: 40-50 mg
Light: 10 – 20 mg
Common: 20 – 30 mg
Strong: 30 – 40 mg
Threshold: 10 mg
Duration
Onset: 0.75-1.5 h
After Effects: 1-12 h
Harm Reduction
Check interactions before mixing substances, pay attention to dose spacing and hydration, and treat all dosage guidance as approximate rather than guaranteed safe.
Sources
Substance data is aggregated from the following public harm-reduction and reference sources.
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Dexmethylphenidate - Treoir substaint DrugsPRO
Dexmethylphenidate: Dexmethylphenidate is the more pharmacologically active enantiomer of methylphenidate, classified as a central nervous system stimulant and norepinephrine-dopamine reuptake inhibitor. Approved for medical use in the United States in 2001 and sold under the brand name Focalin, it