Library
O-PCP
O-PCP has a heavier physical body-load than classic PCP analogues, with users reporting muscle soreness, flu-like malaise, and caustic crystals that irritate mucous membranes. First appeared on European grey-market vendors in early 2025; community reports place potency between ketamine and PCP but with a more sedating body-load and a shorter plateau (approximately 1-2 hours). There is speculation about possible μ-opioid receptor activity based on structural similarity to 3-HO-PCP, though this remains unconfirmed in humans. The powder is hygroscopic and electrostatically clingy; volumetric dosing in propylene glycol or ethanol-water solution (10 mg/mL) is strongly recommended to avoid milligram-scale dosing errors. Cross-tolerance with other arylcyclohexylamines develops rapidly; spacing sessions by at least 7 days is advised to restore baseline NMDA receptor sensitivity.
Also known as: 2-keto-pcp, 2′-Oxo‑PCP
Classification
- Chemical: Arylcyclohexylamine
- Psychoactive: Dissociative
- Tag: Hallucinogen
- Tag: Research-Chemical
Effects
- Physical Disconnection
- Sedation
- Analgesia
- Somatic Heaviness
- Pain Relief
- Numbness
- Cognitive Disconnection
- Depersonalization
- Motor Control Loss
- Time Distortion
- Euphoria
- Dissociation
- Visual Acuity Suppression
- Open Eye Visuals
- Visual Snow
- Disinhibition
- Tactile Suppression
- Double Vision
Routes of Administration
Oral
Dosage
- Threshold: 3 mg
- Light: 3-8 mg
- Common: 8-18 mg
- Strong: 18-35 mg
- Heavy: 35 mg+
Duration
- Onset: 0.33-0.67 h
- Peak: 0.8-2 h
- Offset: 1-2 h
- After Effects: 4-12 h
- Total Duration: 3-6 h
Insufflated
Dosage
- Threshold: 2 mg
- Light: 2-6 mg
- Common: 6-12 mg
- Strong: 12-22 mg
- Heavy: 22 mg+
Duration
- Onset: 0.17-0.33 h
- Peak: 0.5-1.5 h
- Offset: 1.5-3 h
- After Effects: 3-10 h
- Total Duration: 3-5 h
Vaporized / Inhaled
Dosage
- Threshold: 3 mg
- Light: 3-8 mg
- Common: 8-15 mg
- Strong: 15-25 mg
- Heavy: 25 mg
Duration
- Onset: 0.08-0.25 h
- Peak: 0.8-2 h
- Offset: 1-2 h
- After Effects: 1-8 h
Rectal (Boofed)
Dosage
- Threshold: 2 mg
- Light: 2-5 mg
- Common: 5-15 mg
- Strong: 15-30 mg
- Heavy: 30 mg
Duration
- Onset: 0.25-0.5 h
- Peak: 0.8-2 h
- Offset: 1-2 h
- After Effects: 1-8 h
Intramuscular
Dosage
- Threshold: 1 mg
- Light: 1-4 mg
- Common: 4-10 mg
- Strong: 10-18 mg
- Heavy: 18 mg+
Duration
- Onset: 0.08-0.25 h
- Peak: 0.5-1.5 h
- Offset: 1.5-3 h
- After Effects: 1-8 h
- Total Duration: 3-5 h
Vaporized
Dosage
- Heavy: 25 mg+
- Light: 3–8 mg
- Common: 8–15 mg
- Strong: 15–25 mg
- Threshold: 3 mg
Duration
- Onset: 0.08-0.33 h
- Peak: 0.5-1.5 h
- Offset: 1.5-3 h
- After Effects: 2-8 h
- Total Duration: 2-4 h
Rectal
Dosage
- Heavy: 30 mg+
- Light: 2–5 mg
- Common: 5–15 mg
- Strong: 15–30 mg
- Threshold: 2 mg
Duration
No data available for this section yet.
Harm Reduction
Check interactions before mixing substances, pay attention to dose spacing and hydration, and treat all dosage guidance as approximate rather than guaranteed safe.
Sources
Substance data is aggregated from the following public harm-reduction and reference sources.
Links
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