Library
25I-NBOH
25I-NBOH is a synthetic psychedelic of the substituted phenethylamine class, specifically an N-benzylated derivative of 2C-I. First synthesized in 2006 by a team led by David Nichols at Purdue University, it is a close structural analog of 25I-NBOMe and is reported to share most of its properties, though with moderately reduced potency and a shorter duration. It is a known metabolite of 25I-NBOMe and has also been encountered as a designer drug.
Also known as: Cimbi-27, Nboh-2c-i, 2C-I-NBOH
Classification
- Chemical: Phenethylamine
- Psychoactive: Psychedelic
- Tag: Hallucinogen
- Tag: NBOH
- Tag: Research-Chemical
- Tag: Substituted phenethylamine
- Tag: Tentative
Effects
- Pupil Dilation
- Stimulation
- Restlessness
- Muscle Tension
- Temperature Regulation Suppression
- Mentalphysical Stimulation
- Introspection
- Euphoria
- Empathy Enhancement
- Confusion
- Ego Dissolution
- Wakefulness
- Appetite Suppression
- Tactile Enhancement
- Color Enhancement
- Brightened Color
- Closedopen Eye Visuals
- Enhanced Tactile Sensation
Routes of Administration
Sublingual
Dosage
- Heavy: 900 ug
- Light: 150 – 400 µg
- Common: 500 – 800 µg
- Strong: 900 – 1 400 µg
- Threshold: 50 – 100 µg
Duration
- Onset: 0.08-0.75 h
- Comeup: 0.5-1.5 h
- Peak: 2-3.5 h
- Offset: 1.5-2.5 h
- After Effects: 3-12 h
- Total Duration: 6-10 h
Oral
Dosage
- Common: 600 – 1 000 µg
- Light: 300 – 600 µg
- Strong: 600 ug
- Threshold: 150 – 300 µg
- Heavy: >1 600 µg (markedly higher physiological stress)
Duration
- Onset: 0.33-0.75 h
- Peak: 2-4 h
- Offset: 4-7 h
- After Effects: 7-24 h
- Total Duration: 6-10 h
Buccal
Dosage
- Heavy: 800 ug
- Light: 150 – 400 µg
- Common: 400 – 800 µg
- Strong: 800 – 1 300 µg
- Threshold: 50 – 100 µg
Duration
No data available for this section yet.
Harm Reduction
Check interactions before mixing substances, pay attention to dose spacing and hydration, and treat all dosage guidance as approximate rather than guaranteed safe.
Sources
Substance data is aggregated from the following public harm-reduction and reference sources.
Links
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