2-AI is a rigid amphetamine analogue that surfaced as a research chemical in the early 2000s. Reports describe mild, functional stimulation with minimal euphoria. Toxicology data remain sparse and some jurisdictions regulate it alongside amphetamine analogues. In vitro studies show robust activity at NET (EC50 approximately 0.14 uM) and DAT (EC50 approximately 0.31 uM) with negligible SERT activity. Start with allergy tests and conservative doses as individual responses vary widely.
Also known as: Su 8629, 2-indanamine, 2-aminoindan, Pink champagnes, 2-aminoindane, 2,3‑dihydro‑1H‑inden‑2‑amine
Classification
Chemical: Aminoindane
Psychoactive: Stimulant
Tag: Habit-Forming
Tag: Research-Chemical
Tag: Tentative
Effects
Stimulation
Pain Relief
Teeth Grinding
Increased Heart Rate
Increased Perspiration
Insomnia
Euphoria
Focus Enhancement
Thought Acceleration
Analysis Enhancement
Wakefulness
Motivation Enhancement
Appetite Suppression
Increased Music Appreciation
Dehydration
Increased Sexuality
Visual And Auditory Hallucinations
Acuity Enhancement
Routes of Administration
Oral
Dosage
Threshold: 3-5 mg
Light: 5-20 mg
Common: 20-60 mg
Strong: 60-100 mg
Heavy: 100+ mg
Duration
Onset: 0.25-0.75 h
Comeup: 0.5-1 h
Peak: 0.5-1.5 h
Offset: 1-2 h
After Effects: 1-6 h
Total Duration: 2-4 h
Insufflated
Dosage
Threshold: 5 mg
Light: 5-15 mg
Common: 15-40 mg
Strong: 40-80 mg
Heavy: 80+ mg
Duration
Onset: 0.08-0.25 h
Comeup: 0.25-0.5 h
Peak: 0.5-1.5 h
Offset: 0.5-1.5 h
After Effects: 1-6 h
Total Duration: 1.5-3 h
Rectal
Dosage
Threshold: 10 mg
Light: 10-40 mg
Common: 40-100 mg
Strong: 100-200 mg
Heavy: 200+ mg
Duration
Onset: 0.08-0.17 h
Comeup: 0.25-0.5 h
Peak: 0.5-1.5 h
Offset: 1-2 h
After Effects: 1-6 h
Total Duration: 2-4 h
Harm Reduction
Check interactions before mixing substances, pay attention to dose spacing and hydration, and treat all dosage guidance as approximate rather than guaranteed safe.
Sources
Substance data is aggregated from the following public harm-reduction and reference sources.
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2-AI - מדריך חומרים של DrugsPRO
2-AI: 2-AI is a rigid amphetamine analogue that surfaced as a research chemical in the early 2000s. Reports describe mild, functional stimulation with minimal euphoria. Toxicology data remain sparse and some jurisdictions regulate it alongside amphetamine analogues. In vitro studies show robust acti
