3-הידרוקסיפנאזפאם

3-Hydroxyphenazepam is a potent designer benzodiazepine and active metabolite of phenazepam and cinazepam. It is 5-10 times more potent than diazepam and has diminished muscle relaxant properties compared to phenazepam while retaining strong sedative and anxiolytic effects. Recreational doses carry high risk of blackouts, amnesia, and respiratory depression, especially when combined with other CNS depressants. Due to its long half-life and potency, volumetric dosing is strongly recommended. Tolerance and dependence develop rapidly with repeated use, and abrupt cessation can cause life-threatening withdrawal seizures.

Also known as: Hpnz, 3-hop, 3-oh-p, 3ohphenazepam, 3-ho-phenazepam

Classification

Chemical: Benzodiazepine
Psychoactive: Depressant
Tag: Anxiolytic
Tag: GABAergic
Tag: Habit-Forming
Tag: Research-Chemical
Tag: Sedative
Tag: Tentative

Effects

Sedation
Muscle Relaxation
Incoordination
Impaired Balance
Fatigue
Anxiety Suppression
Amnesia
Motor Control Loss
Cognitive Euphoria
Emotion Suppression
Thought Deceleration
Disinhibition
Dulled Perception

Routes of Administration

Oral

Dosage

Threshold: 0.1 mg
Light: 0.25-0.5 mg
Common: 0.5-1.5 mg
Strong: 1.5-3 mg
Heavy: 2-4 mg

Duration

Onset: 0.17-1 h
Comeup: 0.5-1.5 h
Peak: 2-6 h
Offset: 6-14 h
After Effects: 12-24 h
Total Duration: 8-14 h

Harm Reduction

Check interactions before mixing substances, pay attention to dose spacing and hydration, and treat all dosage guidance as approximate rather than guaranteed safe.

Sources

Substance data is aggregated from the following public harm-reduction and reference sources.

Links

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