פוסאזפאם

Fosazepam is a water-soluble phosphate ester derivative of diazepam with approximately 10-fold lower potency (100 mg fosazepam equals 10 mg diazepam). It is a prodrug that is metabolized to desmethyldiazepam (nordiazepam), which has a very long elimination half-life of approximately 72 hours. This long-acting metabolite can cause extended sedation and accumulation with repeated dosing. Clinical trials showed it suppresses deep sleep stages while increasing light sleep duration. Not recommended for use as a hypnotic due to residual morning sedation.

Classification

Chemical: Benzodiazepine
Psychoactive: Depressant
Tag: Anxiolytic
Tag: GABAergic
Tag: Habit-Forming
Tag: Muscle Relaxant
Tag: Prodrug
Tag: Sedative

Effects

Sedation
Muscle Relaxation
Incoordination
Impaired Balance
Motor Impairment
Anxiety Suppression
Amnesia
Drowsiness
Motor Control Loss
Thought Deceleration
Emotion Suppression
Disinhibition
Dulled Perception

Routes of Administration

Oral

Dosage

Light: 30-50 mg
Common: 50-100 mg
Strong: 100-150 mg
Heavy: 150 mg
Threshold: 2–5 mg (very tentative)

Duration

Onset: 0.5-1.5 h
Comeup: 1-2 h
Peak: 2-4 h
Offset: 6-12 h
After Effects: 12-72 h
Total Duration: 6-12 h

Harm Reduction

Check interactions before mixing substances, pay attention to dose spacing and hydration, and treat all dosage guidance as approximate rather than guaranteed safe.

Sources

Substance data is aggregated from the following public harm-reduction and reference sources.

dose.wiki

Links

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