Library

MCPP

meta-Chlorophenylpiperazine (also known as mCPP) is a stimulant drug of the phenylpiperazine class. It was first synthesized as one in a series of potential novel antihistamines by Thomas H. Wicker Jr. in 1951 as part of his doctoral work at the University of Florida. Unlike many other stimulants like amphetamine, mCPP is generally considered to be unpleasant. mCPP is notable for inducing anxiety, and causing migraines and severe headaches. mCPP is occasionally encountered as an adulterant in street MDMA.

MCPP molecular structure
MCPP molecular structure diagram from the DrugsPRO substance library.

Also known as: Cpp, 3-cpp, metachlorophenylpiperazine

Classification

  • Chemical: Piperazine
  • Psychoactive: Stimulant
  • Tag: Research-Chemical
  • Tag: substituted piperazine
  • Tag: Tentative

Effects

  • Increased Heart Rate
  • Stimulation
  • Nausea
  • Jaw Tension
  • Insomnia
  • Restlessness
  • Talkativeness
  • Alertness Enhancement
  • Euphoria
  • Sociability Enhancement
  • Anxiety
  • Empathy Enhancement
  • Light Sensitivity
  • Increased Music Appreciation
  • Auditory Enhancement
  • Blurred Vision
  • Brightness Enhancement
  • Contrast Enhancement

Routes of Administration

Oral

Dosage

  • Threshold: 15 mg
  • Heavy: 150 mg
  • Common: 50-120 mg
  • Light: 20-50 mg
  • Strong: 120-150 mg

Duration

  • Onset: 0.3-1 h
  • Comeup: 0.3-1 h
  • Peak: 2-4 h
  • Offset: 3-8 h

Harm Reduction

Check interactions before mixing substances, pay attention to dose spacing and hydration, and treat all dosage guidance as approximate rather than guaranteed safe.

Sources

Substance data is aggregated from the following public harm-reduction and reference sources.

Links

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MCPP - מדריך חומרים של DrugsPRO

MCPP: meta-Chlorophenylpiperazine (also known as mCPP) is a stimulant drug of the phenylpiperazine class. It was first synthesized as one in a series of potential novel antihistamines by Thomas H. Wicker Jr. in 1951 as part of his doctoral work at the University of Florida. Unlike many other stimula

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