Very little pharmacological or toxicological data exists. Based on structural similarity to mCPP and TFMPP, this compound likely acts as a non-selective serotonin receptor agonist and serotonin releaser. These phenylpiperazines are notorious for producing nausea, migraines, anxiety, and dysphoria rather than euphoria. Severe reactions including hypertension, hyponatremia, and seizures have been reported with related piperazines. The synthesis and anorexigenic properties were described in a 1972 patent, but human metabolism, effective dosing, and long-term safety remain largely uncharacterized.
Also known as: 3,4-cfp, 3cl-4f-p, Kleferein, 3-chloro-4-fluoro-piperein, CFPP, Phenylpiperazine, 3‑chloro‑4‑fluoro‑, 3-Cl-4-FPP, 3-Chloro-4-fluorophenylpiperazine
Classification
Chemical: Piperazine
Psychoactive: Entactogen
Psychoactive: Stimulant
Tag: Phenylpiperazine
Tag: Research-Chemical
Effects
Physical Stimulation
Restlessness
Insomnia
Teeth Grinding
Pupil Dilation
Increased Perspiration
Anxiety
Dysphoria
Mood Lift
Empathy Enhancement
Panic
Euphoria
Visual Distortion
Open Eye Visuals
Patterning
Light Sensitivity
Appetite Suppression
Decreased Libido
Routes of Administration
Oral
Dosage
Threshold: 20 mg
Light: 20 – 50 mg
Common: 50 – 100 mg
Strong: 100 – 150 mg
Heavy: 150 mg +
Duration
Onset: 0.33-1 h
Peak: 1-3 h
Offset: 1-2 h
After Effects: 5-11 h
Total Duration: 4-7 h
Insufflated
Dosage
Threshold: 5 mg
Light: 5 – 15 mg
Common: 15 – 40 mg
Strong: 40 – 70 mg
Heavy: 70 mg +
Duration
Onset: 0.08-0.25 h
Peak: 0.5-2 h
Offset: 1-2 h
After Effects: 4-10 h
Total Duration: 3.5-6 h
Harm Reduction
Check interactions before mixing substances, pay attention to dose spacing and hydration, and treat all dosage guidance as approximate rather than guaranteed safe.
Sources
Substance data is aggregated from the following public harm-reduction and reference sources.
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3,4-CFPP - DrugsPRO vodič za tvari
3,4-CFPP: Very little pharmacological or toxicological data exists. Based on structural similarity to mCPP and TFMPP, this compound likely acts as a non-selective serotonin receptor agonist and serotonin releaser. These phenylpiperazines are notorious for producing nausea, migraines, anxiety, and dy
