Library
4-MEC
4-MEC is a substituted cathinone with stimulant and entactogen properties, structurally related to mephedrone. It has been marketed alone or blended with other cathinones under names such as "NRG-2" and has been identified as an active ingredient in counterfeit ecstasy tablets in some countries. Compared to mephedrone, it is considered less potent with a more pronounced stimulant character. Little is known about its safety profile.
Also known as: Nrg-2, 4-methylethcathinone, 4-methyl-N-ethylcathinone, 4-MeEC
Classification
- Chemical: Cathinone
- Psychoactive: Entactogen
- Psychoactive: Stimulant
- Tag: Habit-Forming
- Tag: Research-Chemical
Effects
- Stimulation
- Increased Perspiration
- Bruxism
- Itchiness
- Increased Energyalertness
- Decreased Need For Sleep
- Euphoria
- Irritability
- Sociability Enhancement
- Wakefulness
- Increased Sociability
- Mood Lift
- Increased Libido
- Appetite Suppression
- Auditory Hallucination
- External Hallucination
- Increased Sexuality
- Visual And Auditory Hallucinations
Routes of Administration
Insufflated
Dosage
- Heavy: 150+ mg
- Light: 25 – 40 mg
- Common: 40 – 100 mg
- Strong: 100 – 150 mg
- Threshold: 25 mg
Duration
- Onset: 0.08-0.25 h
- Peak: 0.5-1 h
- Offset: 1-3 h
- After Effects: 1-4 h
- Total Duration: 2-4 h
Oral
Dosage
- Light: 50 – 100 mg
- Common: 100 – 200 mg
- Strong: 150-200 mg
- Threshold: 50 mg
- Heavy: 200+ mg
Duration
- After Effects: 2-4 h
- Onset: 0.17-0.75 h
- Peak: 1-2 h
- Offset: 2-4 h
- Total Duration: 3-6 h
Intravenous
Dosage
- Heavy: 100+ mg
- Light: 10-30 mg
- Common: 30-60 mg
- Strong: 60-100 mg
- Threshold: 5 mg
Duration
- Onset: 0-0.03 h
- Peak: 0.08-0.25 h
- Offset: 0.5-1.5 h
- After Effects: 1-4 h
- Total Duration: 1-2 h
Harm Reduction
Check interactions before mixing substances, pay attention to dose spacing and hydration, and treat all dosage guidance as approximate rather than guaranteed safe.
Sources
Substance data is aggregated from the following public harm-reduction and reference sources.
Links
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