CBNA (cannabinolic acid) is the carboxylated precursor of cannabinol (CBN), formed when THCA oxidizes. It is produced naturally during storage and aging of cannabis, or rapidly when heated above ~110°C. CBNA itself has minimal affinity for CB1/CB2 receptors and is regarded as non-intoxicating. Limited animal research suggests mild anti-inflammatory and analgesic activity; anecdotal human use points to gentle sedation similar to low-dose CBN. Pharmacokinetic and toxicological data are sparse due to scarcity on the recreational market.
CBNA molecular structure diagram from the DrugsPRO substance library.
Also known as: Cbna-c5, Cannabinol acid, Cannabinolic acid, 2-carboxy-cannabinol
Classification
Chemical: Cannabinoid
Chemical: Medicine
Psychoactive: Nootropic
Tag: Supplement
Effects
Physical Relaxation
Sedation
Subtle Body Warmth
Mild Analgesia
Dry Mouth
Muscle Relaxation
Anxiety Suppression
Minimal Cognitive Impairment
Minimal Euphoria
Drowsiness
Routes of Administration
Oral
Dosage
Threshold: 5 mg
Light: 10 – 25 mg
Common: 25 – 50 mg
Strong: 50 – 100 mg
Heavy: 100 mg +
Duration
Onset: 0.5-1.5 h
Peak: 1.5-3 h
Offset: 1-2 h
After Effects: 5-12 h
Total Duration: 4-8 h
Sublingual
Dosage
Threshold: 2 mg
Light: 5 – 15 mg
Common: 15 – 30 mg
Strong: 30 – 60 mg
Heavy: 60 mg +
Duration
Onset: 0.17-0.5 h
Peak: 1.5-3 h
Offset: 2.5-4 h
After Effects: 4-10 h
Total Duration: 3.5-7 h
Harm Reduction
Check interactions before mixing substances, pay attention to dose spacing and hydration, and treat all dosage guidance as approximate rather than guaranteed safe.
Sources
Substance data is aggregated from the following public harm-reduction and reference sources.
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CBNA - DrugsPRO vodič za tvari
CBNA: CBNA (cannabinolic acid) is the carboxylated precursor of cannabinol (CBN), formed when THCA oxidizes. It is produced naturally during storage and aging of cannabis, or rapidly when heated above ~110°C. CBNA itself has minimal affinity for CB1/CB2 receptors and is regarded as non-intoxicating.