LSD is a semisynthetic psychedelic of the lysergamide class, first synthesized by Albert Hofmann in 1938 from ergot alkaloids, with its psychoactive properties discovered in 1943. It is perhaps the most widely researched and culturally influential psychedelic substance, having played a central role in the 1960s counterculture movement. LSD is among the most potent psychoactive compounds known, producing effects at microgram doses. It is considered non-addictive with extremely low toxicity relative to dose.
LSD molecular structure diagram from the DrugsPRO substance library.
Also known as: L, Cid, Gel, Lucy, Kiselina
Classification
Chemical: Lysergamide
Psychoactive: Psychedelic
Tag: Common
Effects
Spontaneous Tactile Sensations
Stimulation
Nausea
Creativity Enhancement
Increased Heart Rate
Laughter
Time Distortion
Introspection
Dejavu
Multiple Thought Streams
Conceptual Thinking
Ego Suppression Loss And Death
Hallucinations
Visual Drifting
Tracers
After Images
Color Shifting
Scenery Slicing
Routes of Administration
Oral
Dosage
Heavy: 300 ug
Light: 10 – 50 µg
Common: 50 – 150 µg
Strong: 150 – 300 µg
Threshold: 10 ug
Duration
Onset: 0.33-0.67 h
Comeup: 0.75-1.5 h
Peak: 3-5 h
Offset: 3-5 h
After Effects: 12-48 h
Sublingual
Dosage
Heavy: 300 ug
Light: 15 – 75 µg
Common: 75 – 150 µg
Strong: 150 – 300 µg
Threshold: 15 ug
Duration
Onset: 0.25-0.5 h
Comeup: 0.75-1.5 h
Peak: 3-5 h
Offset: 3-5 h
After Effects: 12-48 h
Harm Reduction
Check interactions before mixing substances, pay attention to dose spacing and hydration, and treat all dosage guidance as approximate rather than guaranteed safe.
Sources
Substance data is aggregated from the following public harm-reduction and reference sources.
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LSD - DrugsPRO vodič za tvari
LSD: LSD is a semisynthetic psychedelic of the lysergamide class, first synthesized by Albert Hofmann in 1938 from ergot alkaloids, with its psychoactive properties discovered in 1943. It is perhaps the most widely researched and culturally influential psychedelic substance, having played a central