Nefazodone, sold formerly under the brand names Serzone, Dutonin, and Nefadar among others, is an atypical antidepressant medication which is used in the treatment of depression and for other uses. Nefazodone was withdrawn in most countries by 2004 due to liver toxicity. In December 2021, it was published that despite shortage it is still available in the United States. As of February 2026 it is available in the United States in generic form. The medication is taken by mouth.
Nefazodon molecular structure diagram from the DrugsPRO substance library.
Classification
Chemical: Medicine
Psychoactive: Depressant
Tag: Antidepressant
Effects
Sedation
Motor Impairment
Reduced Anxiety
Anxiety Suppression
Dulled Perception
Routes of Administration
No route information available yet.
Harm Reduction
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Sources
Substance data is aggregated from the following public harm-reduction and reference sources.
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Nefazodone - DrugsPRO vodič za tvari
Nefazodone: Nefazodone, sold formerly under the brand names Serzone, Dutonin, and Nefadar among others, is an atypical antidepressant medication which is used in the treatment of depression and for other uses. Nefazodone was withdrawn in most countries by 2004 due to liver toxicity. In December 2021