R6890, sometimes known as spirochlorphine, is an opioid analgesic and a member of the spiropiperidine family of agents. The first known mention of this compound was in 1977. Other examples of agents from this class are Ro64-6198 and Ro65-6570. Brorphine also has a similar structure. It has been sold as a designer drug, and was proposed for placement on the Schedule 1 list in the USA on 1 July 2026.
Spíróklórfín molecular structure diagram from the DrugsPRO substance library.
Also known as: R6890
Classification
Chemical: Benzimidazolone opioid
Chemical: Opioid
Psychoactive: Depressant
Tag: Orphine
Effects
Sedation
Motor Impairment
Respiratory Depression
Constipation
Pupil Constriction
Itchiness
Reduced Anxiety
Euphoria
Anxiety Suppression
Dulled Perception
Routes of Administration
No route information available yet.
Harm Reduction
Check interactions before mixing substances, pay attention to dose spacing and hydration, and treat all dosage guidance as approximate rather than guaranteed safe.
Sources
Substance data is aggregated from the following public harm-reduction and reference sources.
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Spirochlorphine - DrugsPRO efnisleiðsögn
Spirochlorphine: R6890, sometimes known as spirochlorphine, is an opioid analgesic and a member of the spiropiperidine family of agents. The first known mention of this compound was in 1977. Other examples of agents from this class are Ro64-6198 and Ro65-6570. Brorphine also has a similar structure.