Library
AMB-FUBINACA
• AMB-FUBINACA is among the most potent synthetic cannabinoids known (CB1 K i ≈0.9 nM). A few milligrams can dose hundreds of people; weighing with a scale no better than 1 mg is unsafe—volumetric or pre-dilution onto inert herb is essential.
• Responsible for >50 fatalities in New Zealand (2017–2019) and the 2016 “zombie” outbreak in Brooklyn, USA. Deaths often involve seizures, hyperthermia, pulmonary edema and cardiac arrest.
• Many ‘spice’, ‘K2’, ‘24K Gold’ or ‘AK-47’ herbal blends have highly variable hotspots; even mixing cannot guarantee uniform concentration.
• Metabolized mainly by CYP3A4; strong inhibitors (e.g., ketoconazole, grapefruit) may dramatically prolong and intensify effects.
• No known antidote; treatment is supportive (benzodiazepines for agitation/seizure, IV fluids & cooling for hyperthermia).
Also known as: Amb
Classification
- Chemical: Cannabinoid
- Chemical: Medicine
- Psychoactive: Depressant
- Tag: Habit-Forming
- Tag: Hallucinogen
- Tag: Research-Chemical
Effects
- Tac Tachycardia Palpitations
- Dry Mouth
- Nausea Projectile Vomiting
- Muscle Rigidity Or Catatonia
- Seizures At Highunknown Doses
- Nausea
- Intense Rapid Cannabislike Intoxication
- Euphoria Or Dysphoria Switching Rapidly
- Profound Shortterm Memory Suppression
- Time Dilation
- Severe Anxiety Panic
- Confusion And Dissociation
- Closedeye Visuals At Higher Doses
- Dulled Perception
- Internal Hallucination
- External Hallucination
- Auditory Hallucination
- Drifting
Routes of Administration
Smoked
Dosage
- Threshold: <50 µg
- Light: 50–150 µg
- Common: 150–400 µg
- Strong: 400–800 µg
- Heavy: >800 µg
Duration
- Onset: 0.01 h
- Peak: 0.08-0.42 h
- Offset: 0.5-1.5 h
- After Effects: 2-6 h
Vaporized
Dosage
- Threshold: <50 µg
- Light: 50–150 µg
- Common: 150–400 µg
- Strong: 400–800 µg
- Heavy: >800 µg
Duration
- Onset: 0.01 h
- Peak: 0.08-0.42 h
- Offset: 0.5-1.5 h
- After Effects: 2-6 h
Oral
Dosage
- Threshold: 100 ug
- Light: 100–300 µg
- Common: 300–600 µg
- Strong: 600–900 µg
- Heavy: >900 µg
Duration
- Onset: 0.25-0.75 h
- Peak: 0.5-1.5 h
- Offset: 0.5-1.5 h
- After Effects: 2-6 h
Harm Reduction
Check interactions before mixing substances, pay attention to dose spacing and hydration, and treat all dosage guidance as approximate rather than guaranteed safe.
Sources
Substance data is aggregated from the following public harm-reduction and reference sources.
Links
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