Cocaethylene is not found in nature and forms exclusively in the liver through transesterification when cocaine and alcohol are consumed together. It carries 18-25 times greater risk of immediate death compared to cocaine alone. Cocaethylene is more cardiotoxic and hepatotoxic than either parent substance, with increased risk of seizures, liver damage, compromised immune function, and sudden cardiac death. The metabolite has a longer half-life than cocaine, prolonging euphoric effects while significantly increasing health risks. There is no safe dose, and concurrent use of cocaine and alcohol should be avoided.
Kokaetilenas molecular structure diagram from the DrugsPRO substance library.
Also known as: Homocaine, Ethylcocaine
Classification
Chemical: Tropane
Psychoactive: Stimulant
Tag: Alkaloid
Tag: Habit-Forming
Tag: Precursor
Tag: Toxic-metabolite
Effects
Increased Energy
Cardiovascular Stimulation
Enhanced Euphoria
Increased Confidence
Increased Sociability
Reduced Inhibition
Anxiety
Paranoia
Increased Libido
Routes of Administration
Endogenous Formation
Dosage
No data available for this section yet.
Duration
No data available for this section yet.
Harm Reduction
Check interactions before mixing substances, pay attention to dose spacing and hydration, and treat all dosage guidance as approximate rather than guaranteed safe.
Sources
Substance data is aggregated from the following public harm-reduction and reference sources.
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Cocaethylene - DrugsPRO substancijos vadovas
Cocaethylene: Cocaethylene is not found in nature and forms exclusively in the liver through transesterification when cocaine and alcohol are consumed together. It carries 18-25 times greater risk of immediate death compared to cocaine alone. Cocaethylene is more cardiotoxic and hepatotoxic than eit