Phenibut is a depressant and anxiolytic of the gabapentinoid class, structurally derived from the neurotransmitter GABA. Developed in the Soviet Union during the 1960s under Professor V. V. Perekalin, it remains a prescribed pharmaceutical in Russia for conditions including anxiety, insomnia, depression, and PTSD. Outside Russia, it is unapproved for clinical use and typically sold as a nutritional supplement. At common doses, it is noted for producing less drowsiness than other GABAergic substances such as benzodiazepines.
Fenibutas molecular structure diagram from the DrugsPRO substance library.
Also known as: Phgaba, Noofen, Bifren, Fenibut, Anvifen
Classification
Chemical: Gabapentinoid
Psychoactive: Depressant
Psychoactive: Nootropic
Tag: Anxiolytic
Tag: GABA analogue
Tag: GABAergic
Tag: Habit-Forming
Tag: Research-Chemical
Effects
Stimulation And Sedation
Respiratory Depression
Nausea
Increased Perspiration
Stomach Cramps
Headache
Empathy Love And Sociability Enhancement
Information Processing Suppression
Thought Deceleration
Cognitive Euphoria
Motivation Enhancement
Anxiety Suppression
Disinhibition
Dehydration
Appetite Enhancement
Dulled Perception
Open Eye Visuals
Blurred Vision
Routes of Administration
Oral
Dosage
Heavy: 3.5 g
Light: 0.5-1 g
Common: 1-2 g
Strong: 2-3.5 g
Threshold: 0.25 g
Duration
Onset: 1.5-3 h
Comeup: 1.5-3 h
Peak: 3-4 h
Offset: 4-6 h
After Effects: 6-24 h
Harm Reduction
Check interactions before mixing substances, pay attention to dose spacing and hydration, and treat all dosage guidance as approximate rather than guaranteed safe.
Sources
Substance data is aggregated from the following public harm-reduction and reference sources.
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Phenibut - DrugsPRO substancijos vadovas
Phenibut: Phenibut is a depressant and anxiolytic of the gabapentinoid class, structurally derived from the neurotransmitter GABA. Developed in the Soviet Union during the 1960s under Professor V. V. Perekalin, it remains a prescribed pharmaceutical in Russia for conditions including anxiety, insomn