Sufentanil, also known as sufentanyl and by the brand name Sufenta, is an extremely potent synthetic anilidopiperidine opioid analgesic. Sufentanil has a rapid onset and short mechanism and is used medically as an analgesic in surgical procedures or for the management of post-operative pain. Sufentanil is roughly 500 to 1,000 times more potent than pharmaceutical grade morphine and is approximately 10 times more potent than pharmaceutical grade fentanyl. The subjective effects of sufentanil are similar to those of heroin, with the exception that many users report a significantly less euphoric "high" associated with the drug and stronger respiratory depression, sedation and pain relief. Sufentanil is the most potent opioid analgesic currently used in human medicine.
Sufentanilis molecular structure diagram from the DrugsPRO substance library.
Also known as: Dsuvia, Sufenta, Chronogesic
Classification
Chemical: Anilidopiperidine
Chemical: Medicine
Chemical: Opioid
Psychoactive: Depressant
Tag: Habit-Forming
Tag: Pharmaceutical
Tag: Synthetic opioid
Effects
Pain Relief
Respiratory Depression
Sedation
Physical Euphoria
Cough Suppression
Difficulty Urinating
Anxiety Suppression
Reduced Anxiety
Euphoria
Dulled Perception
Routes of Administration
Intravenous
Dosage
Threshold: 0.1 ug
Light: 1-5 ug
Common: 5-10 ug
Strong: 10-25 ug
Heavy: 25 ug
Duration
Onset: 0.02-0.03 h
Peak: 0.1-0.2 h
Offset: 0.25-0.5 h
After Effects: 1-12 h
Epidural
Dosage
Threshold: 1 ug
Light: 10-30 ug
Common: 30-50 ug
Strong: 50-75 ug
Heavy: 75 ug
Duration
Onset: 0.08-0.25 h
Peak: 0.5-1 h
Offset: 1-2 h
After Effects: 2-8 h
Sublingual
Dosage
Threshold: 15 ug
Light: 15-30 ug
Common: 30-60 ug
Strong: 60-90 ug
Heavy: 90 ug
Duration
Onset: 0.17-0.5 h
Peak: 1-1.5 h
Offset: 1-2 h
After Effects: 2-8 h
Oral
Dosage
Common: 5-10 ug
Light: 1-5 ug
Strong: 10-25 ug
Duration
No data available for this section yet.
Harm Reduction
Check interactions before mixing substances, pay attention to dose spacing and hydration, and treat all dosage guidance as approximate rather than guaranteed safe.
Sources
Substance data is aggregated from the following public harm-reduction and reference sources.
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Sufentanil - DrugsPRO substancijos vadovas
Sufentanil: Sufentanil, also known as sufentanyl and by the brand name Sufenta, is an extremely potent synthetic anilidopiperidine opioid analgesic. Sufentanil has a rapid onset and short mechanism and is used medically as an analgesic in surgical procedures or for the management of post-operative p
