Library
JWH-018
JWH-018 is a synthetic cannabinoid of the naphthoylindole class. It gained widespread recognition from 2006 onward as the primary active ingredient in "Spice" brand herbal smoking blends, which were marketed as potpourri and labeled "not for human consumption." The Spice brand became so dominant that the name was eventually adopted as a generic term for all synthetic cannabinoids. JWH-018 produces cannabis-like effects when smoked but carries the heightened risks characteristic of synthetic cannabinoid compounds.
Also known as: Am-678, NA-PIMO
Classification
- Chemical: Cannabinoid
- Chemical: Synthetic cannabinoid
- Tag: Naphthoylindole
Effects
- Spontaneous Tactile Sensations
- Sedation
- Vasodilation
- Pain Relief
- Physical Discomfort
- Tremor
- Euphoria
- Thought Connectivity
- Anxiety
- Paranoia
- Thought Deceleration
- Immersion Enhancement
- Appetite Enhancement
- Dehydration
- Changes In Gravity
- Color Enhancement
- Acuity Suppression
- Closed Eye Visuals
Routes of Administration
Smoked
Dosage
- Light: 0.25 – 1 mg
- Common: 1 – 3 mg
- Threshold: 0.25 mg
- Strong: 3 – 5 mg
- Heavy: 5 mg +
Duration
- Onset: 0.1-0.2 h
- Peak: 0.08-0.5 h
- Offset: 0.1-0.2 h
- After Effects: 1-1.5 h
- Total Duration: 1.5-3 h
Oral
Dosage
- Heavy: 5 mg +
- Light: 0.5 – 1.5 mg
- Common: 1.5 – 3 mg
- Strong: 3 – 5 mg
- Threshold: 0.5 mg
Duration
- Onset: 0.33-1 h
- Peak: 1-2 h
- Offset: 1-2 h
- After Effects: 2-6 h
- Total Duration: 3-6 h
Vaporized
Dosage
- Heavy: 4 mg +
- Light: 0.2 – 0.8 mg
- Common: 0.8 – 2.5 mg
- Strong: 2.5 – 4 mg
- Threshold: 0.2 mg
Duration
No data available for this section yet.
Harm Reduction
Check interactions before mixing substances, pay attention to dose spacing and hydration, and treat all dosage guidance as approximate rather than guaranteed safe.
Sources
Substance data is aggregated from the following public harm-reduction and reference sources.
Links
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