Citicoline

Citicoline (CDP-choline, cytidine 5'-diphosphocholine) is a water soluble nutrient which serves as a precursor to both choline and cytidine within the brain (which later converts to uridine). To humans, choline is an essential nutrient as its role in reducing the risk of neural tube defects, fatty liver disease, and other pathologies have been documented. CDP-choline is one of the three choline-containing phospholipids that can be orally supplemented (the other two being alpha-GPC and phosphatidylcholine).

Also known as: Cdp-choline, Cytidine diphosphate choline

Classification

Chemical: Medicine
Psychoactive: Nootropic
Tag: Ammonium salt
Tag: Cholinergic
Tag: Cognitive-enhancer
Tag: Nucleotide
Tag: Supplement

Effects

Stimulation
Pain Relief
Headache
Body Odor Alteration
Memory Enhancement
Focus Enhancement
Wakefulness
Dream Potentiation
Mindfulness
Addiction Suppression
Acuity Enhancement
Appetite Suppression

Routes of Administration

Oral

Dosage

Threshold: 50 mg
Light: 100-250 mg
Common: 250-1000 mg
Strong: 1000-2000 mg
Heavy: 2000 mg

Duration

Onset: 1-2 h
Comeup: 2-3 h
Peak: 2.5-3.5 h
Offset: 30-40 h
After Effects: 40-60 h

Harm Reduction

Check interactions before mixing substances, pay attention to dose spacing and hydration, and treat all dosage guidance as approximate rather than guaranteed safe.

Sources

Substance data is aggregated from the following public harm-reduction and reference sources.

Links

This static page is intended as a readable non-JS and prerender-friendly library export.

Get the full DrugsPRO experience

Open the interactive DrugsPRO app for search, saved items, interactions, and deeper harm reduction tools.

Get the PRO test kit. The simple, quick and reliable drug checking test kit. Visit https://protestkit.eu