Citicoline (CDP-choline, cytidine 5'-diphosphocholine) is a water soluble nutrient which serves as a precursor to both choline and cytidine within the brain (which later converts to uridine). To humans, choline is an essential nutrient as its role in reducing the risk of neural tube defects, fatty liver disease, and other pathologies have been documented. CDP-choline is one of the three choline-containing phospholipids that can be orally supplemented (the other two being alpha-GPC and phosphatidylcholine).
Citicoline molecular structure diagram from the DrugsPRO substance library.
Classification
Psychoactive: Nootropic
Tag: Ammonium salt
Effects
Stimulation
Increased Heart Rate
Motivation Enhancement
Euphoria
Light Sensitivity
Routes of Administration
Oral
Dosage
Threshold: 50 mg
Heavy: 2000 mg
Common: 250-1000 mg
Light: 100-250 mg
Strong: 1000-2000 mg
Duration
Onset: 1-2 h
Comeup: 2-3 h
Peak: 2.5-3.5 h
Offset: 30-40 h
After Effects: 40-60 h
Harm Reduction
Check interactions before mixing substances, pay attention to dose spacing and hydration, and treat all dosage guidance as approximate rather than guaranteed safe.
Sources
Substance data is aggregated from the following public harm-reduction and reference sources.
This static page is intended as a readable non-JS and prerender-friendly library export.
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Citicoline - DrugsPRO stofgids
Citicoline: Citicoline (CDP-choline, cytidine 5'-diphosphocholine) is a water soluble nutrient which serves as a precursor to both choline and cytidine within the brain (which later converts to uridine). To humans, choline is an essential nutrient as its role in reducing the risk of neural tube defe
