Library

Diclazepam

Diclazepam is a benzodiazepine and functional analog of diazepam (Valium). Leo Sternbach and colleagues at Hoffman-La Roche first synthesized it in 1960, but it is not approved for medical use and is instead sold as a research chemical. In animal models, diclazepam exhibits long-acting anxiolytic, sedative, hypnotic, anticonvulsant, muscle relaxant, and amnestic properties comparable to diazepam. Its efficacy and safety have not been evaluated in humans.

Diclazepam molecular structure
Diclazepam molecular structure diagram from the DrugsPRO substance library.

Also known as: Chlorodiazepam, 2'-chloro-diazepam, Ro5-3448

Classification

  • Chemical: Benzodiazepine
  • Psychoactive: Depressant
  • Tag: Anticonvulsant
  • Tag: Anxiolytic
  • Tag: GABAergic
  • Tag: Habit-Forming
  • Tag: Muscle Relaxant
  • Tag: Sedative

Effects

  • Sedation
  • Respiratory Depression
  • Muscle Relaxation
  • Anxiolytic
  • Sedative
  • Dystaxia
  • Amnesia
  • Anxiety Suppression
  • Thought Deceleration
  • Information Processing Suppression
  • Euphoria
  • Compulsive Redosing
  • Disinhibition
  • Delirious Hallucination
  • Dulled Perception
  • Open Eye Visuals
  • Double Vision
  • Blurred Vision

Routes of Administration

Oral

Dosage

  • Heavy: 4+ mg
  • Light: 0.5 – 1 mg
  • Common: 1 – 2 mg
  • Strong: 2 – 4 mg
  • Threshold: 0.5 mg

Duration

  • Onset: 0.25-1.5 h
  • After Effects: 24-72 h
  • Peak: 2-6 h
  • Offset: 6-24 h
  • Total Duration: 12-24 h

Harm Reduction

Check interactions before mixing substances, pay attention to dose spacing and hydration, and treat all dosage guidance as approximate rather than guaranteed safe.

Sources

Substance data is aggregated from the following public harm-reduction and reference sources.

Links

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Diclazepam - DrugsPRO stofgids

Diclazepam: Diclazepam is a benzodiazepine and functional analog of diazepam (Valium). Leo Sternbach and colleagues at Hoffman-La Roche first synthesized it in 1960, but it is not approved for medical use and is instead sold as a research chemical. In animal models, diclazepam exhibits long-acting a

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