Levomethorfan

Levomethorphan is a potent opioid analgesic that has never been marketed pharmaceutically. It is the L-stereoisomer of racemethorphan and acts as a prodrug to levorphanol, being demethylated by liver enzymes to its active form. Approximately five times more potent than morphine, levomethorphan carries significant risks of respiratory depression, addiction, and overdose. Due to its metabolism to levorphanol (which has SNRI properties), levomethorphan poses a serious risk of serotonin syndrome when combined with MAOIs, SSRIs, SNRIs, or other serotonergic drugs. It is a Schedule II controlled substance in the United States.

Also known as: Lvm, Ro 1-5470/6, L-methorphan, Levometorfano, Levomethorphanum

Classification

Chemical: Morphinan
Chemical: Opioid
Psychoactive: Depressant
Tag: Research-Chemical

Effects

Pain Relief
Sedation
Respiratory Depression
Itching
Nausea
Physical Euphoria
Euphoria
Cognitive Euphoria
Anxiety Suppression
Compulsive Redosing
Dissociation
Dysphoria
Dulled Perception
Decreased Libido
Increased Music Appreciation
Internal Hallucination
Cognitive Dysphoria
Sound Amplification

Routes of Administration

Oral

Dosage

Threshold: 1-2 mg
Light: 2-5 mg
Common: 5-10 mg
Strong: 10-15 mg
Heavy: 15+ mg

Duration

Onset: 0.33-1 h
Comeup: 0.5-1.5 h
Peak: 1-3 h
Offset: 4-6 h
After Effects: 6-10 h
Total Duration: 4-8 h

Harm Reduction

Check interactions before mixing substances, pay attention to dose spacing and hydration, and treat all dosage guidance as approximate rather than guaranteed safe.

Sources

Substance data is aggregated from the following public harm-reduction and reference sources.

dose.wiki

Links

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