Lisdexamfetamine (also known as lisdextroamphetamine, L-lysine-dextroamphetamine, or lisdexamfetamine dimesylate when under the brand names Elvanse, Tyvense, and Vyvanse) is a stimulant substance of the amphetamine class. It is a "mutual prodrug" (codrug) for d-amphetamine (dextroamphetamine) that is approved for the treatment of attention deficit hyperactivity disorder (ADHD) and moderate to severe binge-eating disorder. Like amphetamine, lisdexamfetamine produces its effects by promoting the release of neurotransmitters dopamine and norepinephrine in the brain.
Lisdexamfetamine molecular structure diagram from the DrugsPRO substance library.
Also known as: Vyvanse, Elvanse, Lisdexamphetamine, Lisdextroamfetamine, Lisdextroamphetamine, LDX, Lisdexamfetamine dimesylate, Dextroamphetamine prodrug, Lisdexamphetamin, L-Lysine-Dextroamphetamine
Classification
Chemical: Amphetamine
Chemical: Medicine
Psychoactive: Stimulant
Tag: Common
Tag: Habit-Forming
Tag: Substituted amphetamine
Effects
Increased Alertness
Reduced Appetite
Flushing Of The Face
Increased Bodily Temperature
Tachycardia
Insomnia
Euphoria
Increased Motivation
Paranoia
Increased Focus
Anxiety
Irritability
Increased Music Appreciation
Increased Libido
Appetite Suppression
Dehydration
Disinhibition
Increased Sexuality
Routes of Administration
Oral
Dosage
Threshold: 5–10 mg
Heavy: 100 mg
Common: 30-50 mg
Light: 20-30 mg
Strong: 50-100 mg
Duration
Onset: 0.67-2 h
Comeup: 0.5-1 h
Peak: 3-5 h
Offset: 6-10 h
After Effects: 10-24 h
Total Duration: 8-14 h
Harm Reduction
Check interactions before mixing substances, pay attention to dose spacing and hydration, and treat all dosage guidance as approximate rather than guaranteed safe.
Sources
Substance data is aggregated from the following public harm-reduction and reference sources.
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Lisdexamfetamine - DrugsPRO stofgids
Lisdexamfetamine: Lisdexamfetamine (also known as lisdextroamphetamine, L-lysine-dextroamphetamine, or lisdexamfetamine dimesylate when under the brand names Elvanse, Tyvense, and Vyvanse) is a stimulant substance of the amphetamine class. It is a "mutual prodrug" (codrug) for d-amphetamine (dextroa
