Trimipramine, sold under the brand name Surmontil among others, is a tricyclic antidepressant (TCA) which is used to treat depression. It has also been used for its sedative, anxiolytic, and weak antipsychotic effects in the treatment of insomnia, anxiety disorders, and psychosis, respectively. The drug is described as an atypical or "second-generation" TCA because, unlike other TCAs, it seems to be a fairly weak monoamine reuptake inhibitor. Similarly to other TCAs, however, trimipramine does have antihistamine, antiserotonergic, antiadrenergic, antidopaminergic, and anticholinergic activities.
Trimipramine molecular structure diagram from the DrugsPRO substance library.
Also known as: Trimipramine maleate, Surmontil
Classification
Chemical: Medicine
Psychoactive: Depressant
Tag: Antidepressant
Tag: Pharmaceutical
Tag: Tricyclic antidepressant
Effects
Sedation
Motor Impairment
Nausea
Headache
Anxiolysis
Insomnia
Reduced Anxiety
Dizziness
Euphoria
Anxiety Suppression
Anxiety
Mood Lift
Dulled Perception
Light Sensitivity
Sexual Dysfunction
Visual Acuity Suppression
Physical Enhancement
Dehydration
Routes of Administration
No route information available yet.
Harm Reduction
Check interactions before mixing substances, pay attention to dose spacing and hydration, and treat all dosage guidance as approximate rather than guaranteed safe.
Sources
Substance data is aggregated from the following public harm-reduction and reference sources.
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Trimipramine - DrugsPRO stofgids
Trimipramine: Trimipramine, sold under the brand name Surmontil among others, is a tricyclic antidepressant (TCA) which is used to treat depression. It has also been used for its sedative, anxiolytic, and weak antipsychotic effects in the treatment of insomnia, anxiety disorders, and psychosis, resp