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5-HO-MET

5-HO-MET, also known as 5-hydroxy-N-methyl-N-ethyltryptamine, is a psychedelic drug of the tryptamine and 5-hydroxytryptamine families related to bufotenin (5-HO-DMT). It is the derivative of bufotenin in which one of the two methyl groups at the amine has been extended to an ethyl group. The drug is also an analogue of methylethyltryptamine (MET), 4-HO-MET (metocin), and 5-MeO-MET. 5-HO-MET was reported as a novel designer drug in Canada in 2025. Its predicted log P is 1.6, relative to 1.2 in the case of bufotenin.

Classification

  • Chemical: Tryptamine
  • Psychoactive: Psychedelic

Effects

  • Dilated Pupils
  • Stimulation
  • Pupil Dilation
  • Introspection
  • Euphoria
  • Confusion
  • Visual Distortion
  • Color Enhancement

Routes of Administration

No route information available yet.

Harm Reduction

Check interactions before mixing substances, pay attention to dose spacing and hydration, and treat all dosage guidance as approximate rather than guaranteed safe.

Sources

Substance data is aggregated from the following public harm-reduction and reference sources.

Links

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5-HO-MET - DrugsPRO stoffveiledning

5-HO-MET: 5-HO-MET, also known as 5-hydroxy-N-methyl-N-ethyltryptamine, is a psychedelic drug of the tryptamine and 5-hydroxytryptamine families related to bufotenin (5-HO-DMT). It is the derivative of bufotenin in which one of the two methyl groups at the amine has been extended to an ethyl group.

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