Acetorphine is an extremely potent synthetic opioid analgesic, up to 8700 times stronger than morphine by weight. It is a derivative of etorphine and was developed in 1966 by the Reckitt research group exclusively for veterinary immobilization of large animals such as elephants, giraffes, and rhinoceros. Despite showing some advantages over etorphine (reduced toxic side effects in giraffes), it was never widely adopted for veterinary use. Acetorphine is Schedule I in the United States and Class A in the UK, prohibited for human use. Human exposure can be fatal even at extremely low doses due to severe respiratory depression.
Acetorfin molecular structure diagram from the DrugsPRO substance library.
Also known as: Acetyletorphine, Acetylpropylorvinol, Acetorfina
Classification
Chemical: Morphinan
Chemical: Opioid
Psychoactive: Depressant
Tag: Habit-Forming
Tag: Oripavine derivative
Tag: Research-Chemical
Tag: Veterinary-only
Effects
Analgesia
Sedation
Respiratory Depression
Physical Euphoria
Nausea
Itchiness
Euphoria
Anxiety Suppression
Sadness
Reduced Anxiety
Cognitive Euphoria
Mood Lift
Dulled Perception
Decreased Libido
Increased Music Appreciation
Cognitive Dysphoria
Internal Hallucination
Closed Eye Visuals
Routes of Administration
Intramuscular
Dosage
Common: Veterinary use only: 0.01-0.03 mg per animal (large mammals)
Duration
No data available for this section yet.
Harm Reduction
Check interactions before mixing substances, pay attention to dose spacing and hydration, and treat all dosage guidance as approximate rather than guaranteed safe.
Sources
Substance data is aggregated from the following public harm-reduction and reference sources.
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Acetorphine - DrugsPRO stoffveiledning
Acetorphine: Acetorphine is an extremely potent synthetic opioid analgesic, up to 8700 times stronger than morphine by weight. It is a derivative of etorphine and was developed in 1966 by the Reckitt research group exclusively for veterinary immobilization of large animals such as elephants, giraffe