DOC

DOC is a psychedelic amphetamine of the DOx family, first synthesized in 1972 at the University of Alberta and later documented by Alexander Shulgin in PiHKAL (1991). It is characterized by its long duration, strong visual effects, and prominent stimulant properties. DOC is highly dose-sensitive and often sold on blotter paper. Its intense body load and potency make it particularly challenging for those inexperienced with psychedelics.

DOC molecular structure diagram from the DrugsPRO substance library.

Also known as: 4-chloro-2,5-DMA

Classification

Chemical: Amphetamine
Chemical: Phenethylamine
Psychoactive: Psychedelic
Psychoactive: Stimulant
Tag: Common
Tag: Hallucinogen
Tag: Research-Chemical
Tag: Substituted amphetamine

Effects

Spontaneous Tactile Sensations
Stimulation
Nausea
Vasoconstriction
Pupil Dilation
Increased Blood Pressure
Empathy Love And Sociability Enhancement
Analysis Enhancement
Thought Acceleration
Time Distortion
Novelty Enhancement
Immersion Enhancement
Tactile Enhancement
Bodily Control Enhancement
Hallucinations
Drifting
Tracers
After Images

Routes of Administration

Oral

Dosage

Heavy: 5.0+ mg
Light: 1 – 1.5 mg
Common: 1.5 – 2 mg
Strong: 3.0–5.0 mg
Threshold: 0.5 – 1 mg

Duration

Onset: 0.5-2.5 h
Comeup: 2-3 h
Peak: 6-12 h
Offset: 8-20 h
After Effects: 6-24 h
Total Duration: 8-20 h

Insufflated

Dosage

Heavy: 3.5 – 4 mg
Light: 0.5 – 1 mg
Common: 1 – 2 mg
Strong: 2.5 – 3.5 mg
Threshold: 0.5 mg

Duration

Onset: 0-0.1 h
Comeup: 0.17-0.5 h
Peak: 2-6 h
Offset: 2-8 h
After Effects: 2-24 h

Harm Reduction

Check interactions before mixing substances, pay attention to dose spacing and hydration, and treat all dosage guidance as approximate rather than guaranteed safe.

Sources

Substance data is aggregated from the following public harm-reduction and reference sources.

Links

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DOC