3,4-CTMP is approximately seven times more potent than methylphenidate and has a significantly longer duration of 6-18 hours. A critical safety concern is its agonist activity at 5-HT2B receptors, which can cause pulmonary hypertension and heart valve fibrosis with repeated use. Insufflation is strongly discouraged as the substance has low water solubility, is extremely caustic to nasal tissues, and has poor absorption leading to delayed onset that increases overdose risk. Users must use precise milligram scales due to the extremely low active doses. The very long onset (1-2 hours) and extended duration require careful dose timing to avoid unwanted sleep disruption and accidental overdoses from premature redosing.
Also known as: 3,4-ctmp, 3,4-dcmp, Dichloromethylphenidate
Classification
Chemical: Phenidate
Psychoactive: Stimulant
Tag: Habit-Forming
Tag: Research-Chemical
Tag: substituted phenidate
Effects
Stimulation
Increased Heart Rate
Vasoconstriction
Teeth Grinding
Headache
Pupil Dilation
Focus Enhancement
Motivation Enhancement
Wakefulness
Thought Acceleration
Analysis Enhancement
Time Distortion
Appetite Suppression
Dehydration
Increased Sexuality
Visual And Auditory Hallucinations
Double Vision
Disinhibition
Routes of Administration
Oral
Dosage
Threshold: 1-2 mg
Light: 2-4 mg
Common: 4-6 mg
Strong: 6-8 mg
Heavy: 6-10 mg
Duration
Onset: 1-2 h
Peak: 3-6 h
Offset: 4-8 h
After Effects: 2-24 h
Harm Reduction
Check interactions before mixing substances, pay attention to dose spacing and hydration, and treat all dosage guidance as approximate rather than guaranteed safe.
Sources
Substance data is aggregated from the following public harm-reduction and reference sources.
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3,4-Dichloromethylphenidate - przewodnik po substancji DrugsPRO
3,4-Dichloromethylphenidate: 3,4-CTMP is approximately seven times more potent than methylphenidate and has a significantly longer duration of 6-18 hours. A critical safety concern is its agonist activity at 5-HT2B receptors, which can cause pulmonary hypertension and heart valve fibrosis with repea
