Flutoprazepam is an extremely long-acting benzodiazepine primarily used in Japan for severe insomnia and as an anticonvulsant. It is approximately 4 times more potent than diazepam by weight. The extremely long duration is due to its active metabolite norflurazepam (90 hour half-life), which causes significant accumulation and next-day sedation. Due to the long half-life, effects may not peak until many hours after administration. Has been reported as a date rape drug.
Flutoprazepam molecular structure diagram from the DrugsPRO substance library.
Also known as: Restas, Kb-509, FZP
Classification
Chemical: Benzodiazepine
Psychoactive: Depressant
Tag: Anxiolytic
Tag: GABAergic
Tag: Habit-Forming
Tag: Muscle Relaxant
Tag: Sedative
Effects
Sedation
Muscle Relaxation
Physical Euphoria
Anxiolytic
Sedative
Dystaxia
Anxiety Suppression
Cognitive Euphoria
Motor Control Loss
Amnesia
Emotion Suppression
Delusions Of Sobriety
Disinhibition
Dulled Perception
Routes of Administration
Oral
Dosage
Threshold: 0.5 mg
Light: 0.5-1 mg
Common: 1-2.5 mg
Strong: 2.5-5 mg
Heavy: 5+ mg
Duration
Onset: 0.5-1.5 h
Comeup: 1-2 h
Peak: 2-12 h
Offset: 24-96 h
After Effects: 24-72 h
Total Duration: 60-90 h
Harm Reduction
Check interactions before mixing substances, pay attention to dose spacing and hydration, and treat all dosage guidance as approximate rather than guaranteed safe.
Sources
Substance data is aggregated from the following public harm-reduction and reference sources.
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Flutoprazepam - przewodnik po substancji DrugsPRO
Flutoprazepam: Flutoprazepam is an extremely long-acting benzodiazepine primarily used in Japan for severe insomnia and as an anticonvulsant. It is approximately 4 times more potent than diazepam by weight. The extremely long duration is due to its active metabolite norflurazepam (90 hour half-life)