CRITICAL WARNING: True FXE (3'-Fluoro-2-oxo-PCE, 3-FXE) may have NEVER been available on the recreational market. In April 2023, DrugsData.org revealed that ALL samples they previously identified as FXE actually contained 2F-NENDCK (CanKet, 2'-Fluoro-2-oxo-PCE), a positional isomer differing only by fluorine position on the phenyl ring. True 3-FXE and 2F-NENDCK are nearly impossible to distinguish without advanced analytical methods like NMR spectroscopy. Most user reports, dosage information, and effects attributed to FXE from 2017-2023 were likely describing 2F-NENDCK experiences. As of 2024-2025, some vendors claim to sell true 3-FXE, but independent laboratory verification is essential.
FXE molecular structure diagram from the DrugsPRO substance library.
Also known as: 3-fxe, 3f-o-pce, Fluorexetamine, 3'-fluoro-2-oxo-pce, Fluorexetamin
Classification
Chemical: Arylcyclohexylamine
Psychoactive: Dissociative
Tag: Hallucinogen
Tag: Research-Chemical
Effects
Analgesia
Pain Relief
Incoordination
Sedation
Nystagmus
Numbness
Dissociation
Motor Control Loss
Cognitive Impairment
Anxiety Suppression
Conceptual Thinking
Confusion
Tactile Suppression
Visual Distortion
Double Vision
Pattern Recognition Suppression
Perception Of Bodily Lightness
Open Eye Visuals
Routes of Administration
Oral
Dosage
Heavy: 60+ mg
Light: 10–20 mg
Common: 20–40 mg
Strong: 40–60 mg
Threshold: 5–10 mg
Duration
Onset: 0.25-0.5 h
Peak: 1-3 h
Offset: 2-3 h
After Effects: 6-24 h
Total Duration: 4-6 h
Insufflated
Dosage
Heavy: 50+ mg
Light: 8–15 mg
Common: 15–30 mg
Strong: 30–50 mg
Threshold: 3–8 mg
Duration
Onset: 0.08-0.25 h
Peak: 1-2.5 h
Offset: 1.5-2.5 h
After Effects: 4-24 h
Total Duration: 3-5 h
Harm Reduction
Check interactions before mixing substances, pay attention to dose spacing and hydration, and treat all dosage guidance as approximate rather than guaranteed safe.
Sources
Substance data is aggregated from the following public harm-reduction and reference sources.
This static page is intended as a readable non-JS and prerender-friendly library export.
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FXE - przewodnik po substancji DrugsPRO
FXE: CRITICAL WARNING: True FXE (3'-Fluoro-2-oxo-PCE, 3-FXE) may have NEVER been available on the recreational market. In April 2023, DrugsData.org revealed that ALL samples they previously identified as FXE actually contained 2F-NENDCK (CanKet, 2'-Fluoro-2-oxo-PCE), a positional isomer differing on
