Library

Lisdeksamfetamina

Lisdexamfetamine is a central nervous system stimulant of the amphetamine class, designed as a prodrug of dextroamphetamine. First approved by the FDA in 2007, it was specifically formulated to deter non-oral abuse by requiring metabolic conversion to release its active component. Prescribed for ADHD and binge eating disorder, it produces typical amphetamine effects including stimulation, focus enhancement, and euphoria, but with slower onset and longer duration than conventional amphetamines. Despite its anti-abuse design, it retains significant dependence potential.

Lisdeksamfetamina molecular structure
Lisdeksamfetamina molecular structure diagram from the DrugsPRO substance library.

Also known as: Vyvanse, Elvanse, Tyvense, Lisdexamphetamine, Lisdextroamfetamine, LDX, Lisdexamfetamine dimesylate, Dextroamphetamine prodrug, Lisdexamphetamin, L-Lysine-Dextroamphetamine

Classification

  • Chemical: Amphetamine
  • Chemical: Medicine
  • Psychoactive: Stimulant
  • Tag: Common
  • Tag: Habit-Forming
  • Tag: Substituted amphetamine

Effects

  • Fatigue
  • Temperature Regulation Suppression
  • Dry Mouth
  • Increased Heart Rate
  • Stimulation
  • Nausea
  • Euphoria
  • Anxiety
  • Paranoia
  • Motivation Enhancement
  • Focus Enhancement
  • Analysis Enhancement
  • Hallucinations
  • Appetite Suppression
  • Increased Music Appreciation
  • Increased Libido
  • Dehydration
  • Disinhibition

Routes of Administration

Oral

Dosage

  • Heavy: 90 mg
  • Light: 10 – 30 mg
  • Common: 30 – 60 mg
  • Strong: 60 – 90 mg
  • Threshold: 5–10 mg

Duration

  • Onset: 0.67-2 h
  • Comeup: 0.5-1 h
  • Peak: 3-5 h
  • Offset: 6-10 h
  • After Effects: 10-24 h
  • Total Duration: 8-14 h

Harm Reduction

Check interactions before mixing substances, pay attention to dose spacing and hydration, and treat all dosage guidance as approximate rather than guaranteed safe.

Sources

Substance data is aggregated from the following public harm-reduction and reference sources.

Links

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Lisdexamfetamine - przewodnik po substancji DrugsPRO

Lisdexamfetamine: Lisdexamfetamine (also known as lisdextroamphetamine, L-lysine-dextroamphetamine, or lisdexamfetamine dimesylate when under the brand names Elvanse, Tyvense, and Vyvanse) is a stimulant substance of the amphetamine class. It is a "mutual prodrug" (codrug) for d-amphetamine (dextroa

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