O-PCPr emerged in late 2024 after being mis-sold as O-PCE. User reports describe a steep dose-response curve, rapid onset with upwellings of euphoria, pronounced motor incoordination, bright closed-eye visuals, and a warm euphoria distinct from MXiPr or O-PCE. The headspace is relatively lucid and functional compared to other dissociatives. Analytical work (HR-MS, GC-MS) has begun mapping 2-oxo-PCPr metabolites, but no peer-reviewed human pharmacokinetics exist. Some users report bladder and urinary irritation.
Also known as: 2'-oxo-pcpr, Deschloro-n-propyl-ketamine, 2-Keto-PCPr
Classification
Chemical: Arylcyclohexylamine
Psychoactive: Dissociative
Tag: Hallucinogen
Tag: Research-Chemical
Effects
Physical Disconnection
Analgesia
Suggestibility Enhancement
Pain Relief
Physical Comfort
Incoordination
Cognitive Disconnection
Euphoria
Time Distortion
Motor Control Loss
Conceptual Thinking
Analysis Enhancement
Visual Disconnection
Spatial Disorientation
Internal Hallucination
Tactile Suppression
Perception Of Bodily Lightness
Closed Eye Visuals
Routes of Administration
Insufflated
Dosage
Threshold: 5-10 mg
Light: 10-20 mg
Common: 20-40 mg
Strong: 40-70 mg
Heavy: 70+ mg
Duration
Onset: 0.08-0.25 h
Comeup: 0.17-0.33 h
Peak: 1-3 h
Offset: 2-4 h
After Effects: 4-10 h
Total Duration: 4-7 h
Oral
Dosage
Threshold: 15-25 mg
Light: 25-45 mg
Common: 45-70 mg
Strong: 70-100 mg
Heavy: 100+ mg
Duration
Onset: 0.5-1 h
Comeup: 0.5-1 h
Peak: 1-3 h
Offset: 2-4 h
After Effects: 5-12 h
Total Duration: 5-9 h
Harm Reduction
Check interactions before mixing substances, pay attention to dose spacing and hydration, and treat all dosage guidance as approximate rather than guaranteed safe.
Sources
Substance data is aggregated from the following public harm-reduction and reference sources.
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O-PCPr - przewodnik po substancji DrugsPRO
O-PCPr: O-PCPr emerged in late 2024 after being mis-sold as O-PCE. User reports describe a steep dose-response curve, rapid onset with upwellings of euphoria, pronounced motor incoordination, bright closed-eye visuals, and a warm euphoria distinct from MXiPr or O-PCE. The headspace is relatively luc
