Library

Proskalina

Proscaline is a lesser-known psychedelic of the substituted phenethylamine class, structurally related to mescaline as its 4-propyloxy analog. Its synthesis was first published by David E. Nichols in 1977, and it was later evaluated by Alexander Shulgin, who estimated its potency at roughly five times that of mescaline. Shulgin documented his findings in the 1991 book PiHKAL. It belongs to a series of mescaline analogs including escaline and allylescaline, and appeared on the research chemical market in the 2010s.

Proskalina molecular structure
Proskalina molecular structure diagram from the DrugsPRO substance library.

Also known as: P, 4-propoxy-3,5-dmpea

Classification

  • Chemical: Phenethylamine
  • Psychoactive: Psychedelic
  • Tag: Hallucinogen
  • Tag: Research-Chemical
  • Tag: Scaline
  • Tag: Substituted phenethylamine

Effects

  • Pupil Dilation
  • Temperature Regulation Suppression
  • Stimulation
  • Muscle Tension
  • Tremors
  • Mentalphysical Stimulation
  • Euphoria
  • Empathy Enhancement
  • Irritability
  • Analysis Enhancement
  • Confusion
  • Sociability Enhancement
  • Appetite Suppression
  • Tactile Enhancement
  • Color Enhancement
  • Brightened Color
  • Closedopen Eye Visuals
  • Enhanced Tactile Sensation

Routes of Administration

Oral

Dosage

  • Heavy: 60 mg
  • Light: 10 – 30 mg
  • Common: 30 – 40 mg
  • Strong: 40 – 60 mg
  • Threshold: 10 mg

Duration

  • Onset: 0.5-1 h
  • After Effects: 3-5 h

Harm Reduction

Check interactions before mixing substances, pay attention to dose spacing and hydration, and treat all dosage guidance as approximate rather than guaranteed safe.

Sources

Substance data is aggregated from the following public harm-reduction and reference sources.

Links

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Proscaline - przewodnik po substancji DrugsPRO

Proscaline: Proscaline is a lesser-known psychedelic of the substituted phenethylamine class, structurally related to mescaline as its 4-propyloxy analog. Its synthesis was first published by David E. Nichols in 1977, and it was later evaluated by Alexander Shulgin, who estimated its potency at roug

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