Library

TMA

TMA is a rare synthetic psychedelic amphetamine and the alpha-methylated analog of mescaline. Effects are generally less visual and less euphoric than mescaline, with more unpredictable emotional responses. At higher doses (above 200 mg), Shulgin's research documented potentially antisocial behavioral changes including anger and hostility, which were not observed with mescaline. Effects include mild psychedelic aura, tactile enhancement, and dreamy mental states with minimal visuals at lower doses. There is extremely limited human use history and virtually no modern research.

TMA molecular structure
TMA molecular structure diagram from the DrugsPRO substance library.

Also known as: Tma-1, 3,4,5-tma, Α-methylmescaline, Mescalamphetamine, Trimethoxyamphetamine

Classification

  • Chemical: Amphetamine
  • Chemical: Phenethylamine
  • Psychoactive: Psychedelic
  • Psychoactive: Stimulant
  • Tag: Hallucinogen
  • Tag: Research-Chemical

Effects

  • Nausea
  • Pupil Dilation
  • Increased Heart Rate
  • Stimulation
  • Coldness
  • Insomnia
  • Emotion Enhancement
  • Cognitive Euphoria
  • Conceptual Thinking
  • Anxiety
  • Time Distortion
  • Introspection
  • Tactile Enhancement
  • Visual Patterning
  • Color Enhancement
  • Open Eye Visuals
  • Light Sensitivity
  • Tracers

Routes of Administration

Oral

Dosage

  • Threshold: 50-80 mg
  • Light: 80-120 mg
  • Common: 120-180 mg
  • Strong: 180-225 mg
  • Heavy: 250+ mg

Duration

  • Onset: 1.5-2 h
  • Comeup: 0.5-1 h
  • Peak: 3-5 h
  • Offset: 2-3 h
  • After Effects: 8-14 h
  • Total Duration: 6-8 h

Harm Reduction

Check interactions before mixing substances, pay attention to dose spacing and hydration, and treat all dosage guidance as approximate rather than guaranteed safe.

Sources

Substance data is aggregated from the following public harm-reduction and reference sources.

Links

This static page is intended as a readable non-JS and prerender-friendly library export.

Get the full DrugsPRO experience

Open the interactive DrugsPRO app for search, saved items, interactions, and deeper harm reduction tools.

Get the PRO test kit. The simple, quick and reliable drug checking test kit. Visit https://protestkit.eu

TMA - przewodnik po substancji DrugsPRO

TMA: TMA is a rare synthetic psychedelic amphetamine and the alpha-methylated analog of mescaline. Effects are generally less visual and less euphoric than mescaline, with more unpredictable emotional responses. At higher doses (above 200 mg), Shulgin's research documented potentially antisocial beh

Related pages