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Lisdexanfetamina

Lisdexamfetamine (also known as lisdextroamphetamine, L-lysine-dextroamphetamine, or lisdexamfetamine dimesylate when under the brand names Elvanse, Tyvense, and Vyvanse) is a stimulant substance of the amphetamine class. It is a "mutual prodrug" (codrug) for d-amphetamine (dextroamphetamine) that is approved for the treatment of attention deficit hyperactivity disorder (ADHD) and moderate to severe binge-eating disorder. Like amphetamine, lisdexamfetamine produces its effects by promoting the release of neurotransmitters dopamine and norepinephrine in the brain.

Lisdexanfetamina molecular structure
Lisdexanfetamina molecular structure diagram from the DrugsPRO substance library.

Also known as: Vyvanse, Elvanse, Lisdexamphetamine, Lisdextroamfetamine, Lisdextroamphetamine, LDX, Lisdexamfetamine dimesylate, Dextroamphetamine prodrug, Lisdexamphetamin, L-Lysine-Dextroamphetamine

Classification

  • Chemical: Amphetamine
  • Chemical: Medicine
  • Psychoactive: Stimulant
  • Tag: Common
  • Tag: Habit-Forming
  • Tag: Substituted amphetamine

Effects

  • Increased Alertness
  • Reduced Appetite
  • Flushing Of The Face
  • Increased Bodily Temperature
  • Tachycardia
  • Insomnia
  • Euphoria
  • Increased Motivation
  • Paranoia
  • Increased Focus
  • Anxiety
  • Irritability
  • Increased Music Appreciation
  • Increased Libido
  • Appetite Suppression
  • Dehydration
  • Disinhibition
  • Increased Sexuality

Routes of Administration

Oral

Dosage

  • Threshold: 5–10 mg
  • Heavy: 100 mg
  • Common: 30-50 mg
  • Light: 20-30 mg
  • Strong: 50-100 mg

Duration

  • Onset: 0.67-2 h
  • Comeup: 0.5-1 h
  • Peak: 3-5 h
  • Offset: 6-10 h
  • After Effects: 10-24 h
  • Total Duration: 8-14 h

Harm Reduction

Check interactions before mixing substances, pay attention to dose spacing and hydration, and treat all dosage guidance as approximate rather than guaranteed safe.

Sources

Substance data is aggregated from the following public harm-reduction and reference sources.

Links

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Lisdexamfetamine - Guia de substâncias DrugsPRO

Lisdexamfetamine: Lisdexamfetamine (also known as lisdextroamphetamine, L-lysine-dextroamphetamine, or lisdexamfetamine dimesylate when under the brand names Elvanse, Tyvense, and Vyvanse) is a stimulant substance of the amphetamine class. It is a "mutual prodrug" (codrug) for d-amphetamine (dextroa

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