Nitrazepam

Nitrazepam is a long-acting benzodiazepine hypnotic first synthesized in the late 1950s by Hoffmann-La Roche and introduced medically in 1965 under the brand name Mogadon. It possesses potent sedative, anxiolytic, amnestic, anticonvulsant, and muscle relaxant properties. Nitrazepam is primarily prescribed for short-term treatment of severe insomnia and disabling anxiety, reducing sleep onset time and increasing sleep duration. It is also used in managing myoclonic seizures.

Also known as: Arem, Dreem, Enzed, Konit, Nigap, Mogadon, Nitrazepamum, RO 5-3059, RO 4-5360, N05CD02

Classification

Chemical: Benzodiazepine
Chemical: Medicine
Psychoactive: Depressant
Tag: Anxiolytic
Tag: Habit-Forming
Tag: Sedative

Effects

Respiratory Depression
Temperature Regulation Suppression
Ataxia
Sedation
Muscle Relaxation
Stimulation
Anxiety Suppression
Emotion Suppression
Depression
Anxiety
Cognitive Fatigue
Confusion
Hallucinations
Tactile Hallucination
Double Vision
Dulled Perception
Disinhibition

Routes of Administration

Oral

Dosage

Heavy: 20-30 mg
Light: 2 – 5 mg
Common: 5 – 15 mg
Strong: 15 – 20 mg
Threshold: 2.5 mg

Duration

Onset: 0.17-0.67 h
After Effects: 12-24 h
Peak: 1-4 h
Offset: 6-12 h
Total Duration: 6-12 h

Harm Reduction

Check interactions before mixing substances, pay attention to dose spacing and hydration, and treat all dosage guidance as approximate rather than guaranteed safe.

Sources

Substance data is aggregated from the following public harm-reduction and reference sources.

Links

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