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2,3-XP

2,3-Dimethylphenylpiperazine (2,3-DMPP; code name PAL-218) is a monoamine releasing agent and designer drug of the phenylpiperazine family. It acts as a partial serotonin–norepinephrine releasing agent (SNRA), with EC50Tooltip half-maximal effective concentration (EmaxTooltip maximal efficacy) values of 24 to 26 nM (85%) for serotonin, 13.7 to 56 nM (62%) for norepinephrine, and 1,207 to 1,320 nM (66%) for dopamine (22–96-fold lower than serotonin and norepinephrine). Its possible activities at serotonin receptors were not reported. The drug was first described in the scientific literature by 2009.

Also known as: 1-(2,3-dichlorophenyl)piperazine

Classification

  • Chemical: Piperazine

Effects

  • Stimulation
  • Nausea
  • Increased Heart Rate
  • Insomnia
  • Headache
  • Pupil Dilation
  • Talkativeness
  • Alertness Enhancement
  • Euphoria
  • Anxiety
  • Mood Lift
  • Increased Sociability
  • Light Sensitivity
  • Appetite Suppression
  • Visual Distortion
  • Open Eye Visuals
  • Patterning
  • Blurred Vision

Routes of Administration

No route information available yet.

Harm Reduction

Check interactions before mixing substances, pay attention to dose spacing and hydration, and treat all dosage guidance as approximate rather than guaranteed safe.

Sources

Substance data is aggregated from the following public harm-reduction and reference sources.

Links

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2,3-XP - Ghid de substanțe DrugsPRO

2,3-XP: 2,3-Dimethylphenylpiperazine (2,3-DMPP; code name PAL-218) is a monoamine releasing agent and designer drug of the phenylpiperazine family. It acts as a partial serotonin–norepinephrine releasing agent (SNRA), with EC50Tooltip half-maximal effective concentration (EmaxTooltip maximal efficac

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