Clinical studies using doses up to 800 mg twice daily for 8 weeks have shown good safety with mostly mild gastrointestinal upset and somnolence. Like CBD, CBDV is a moderate inhibitor of several CYP450 enzymes; use caution with narrow-therapeutic-index drugs. Early evidence suggests anticonvulsant, anti-inflammatory and possible nootropic or attention-enhancing properties. Psychoactive effects are generally subtle or absent; some users describe a clear-headed, slightly stimulating sensation of bodily calm. Because extracts often contain other cannabinoids, confirm lab reports to estimate actual CBDV content before dosing.
CBDV molecular structure diagram from the DrugsPRO substance library.
Also known as: Cannabidivarin, Gwp42006, Cannabidivarol, Varinic CBD, CBD-varin
Classification
Chemical: Cannabinoid
Chemical: Medicine
Psychoactive: Nootropic
Tag: Supplement
Tag: Not psychoactive
Effects
Mild Anxiolysis
Decreased Seizure Frequency
Reduced Inflammation Or Pain
Stomach Discomfort
Physical Discomfort
Stimulation
Subtle Mood Elevation
Enhanced Mental Clarity Or Focus
Very Low Or Absent Intoxication
Euphoria
Anxiety Suppression
Increased Focus
Routes of Administration
Oral
Dosage
Threshold: 10 mg
Light: 20 – 50 mg
Common: 50 – 200 mg
Strong: 200 – 400 mg
Heavy: 400 mg+
Duration
Onset: 0.5-2 h
Peak: 2-4 h
Offset: 2-3 h
After Effects: 8-12 h
Total Duration: 6-8 h
Smoked
Dosage
Threshold: 1 mg
Light: 2 – 5 mg
Common: 5 – 15 mg
Strong: 15 – 30 mg
Heavy: 30 mg+
Duration
Onset: 0-0.08 h
Peak: 0.25-1 h
Offset: 1-2 h
After Effects: 2-6 h
Total Duration: 2-4 h
Harm Reduction
Check interactions before mixing substances, pay attention to dose spacing and hydration, and treat all dosage guidance as approximate rather than guaranteed safe.
Sources
Substance data is aggregated from the following public harm-reduction and reference sources.
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CBDV - Ghid de substanțe DrugsPRO
CBDV: Clinical studies using doses up to 800 mg twice daily for 8 weeks have shown good safety with mostly mild gastrointestinal upset and somnolence. Like CBD, CBDV is a moderate inhibitor of several CYP450 enzymes; use caution with narrow-therapeutic-index drugs. Early evidence suggests anticonvul
