Library
1S-LSD
1S-LSD is 1-(3-trimethylsilyl-propionyl)-LSD, a silicon-containing N1-acyl analogue designed to circumvent Germany's NpSG following the 1D-LSD ban in June 2024. Analytical studies confirm it hydrolyzes in vitro and in vivo to LSD-25. User reports and reagent-testing services indicate the blotters do not trigger Ehrlich or DMAB reagents, necessitating laboratory confirmation. Community consensus suggests oral potency is approximately 70 percent of equimolar LSD-25, with a noticeably slower onset but identical plateau once conversion occurs. Silicon-carbon bonds are hydrolytically labile; moisture-exposed tabs may degrade within weeks.
Also known as: 1S‑LSD D‑tartrate, N1‑TMS‑propionyl lysergamide
Classification
- Chemical: Lysergamide
- Psychoactive: Psychedelic
- Tag: Research-Chemical
Effects
- Vasoconstriction
- Physical Energy
- Dilated Pupils
- Stimulation
- Nausea
- Pupil Dilation
- Euphoria
- Giggling
- Time Distortion
- Thought Loop
- Introspection
- Conceptual Thinking
- Visual Enhancement
- Geometric Patterns
- Color Enhancement
- Tracers
- Visual Trails
- Open Eye Visuals
Routes of Administration
Oral / Sublingual (Blotter / Liquid)
Dosage
- Threshold: 15 ug
- Light: 15-50 ug
- Common: 50-170 ug
- Strong: 170-300 ug
- Heavy: 300 ug
Duration
- Onset: 0.75-2 h
- Comeup: 0.5-1.5 h
- Peak: 3-5 h
- Offset: 2-4 h
- After Effects: 6-24 h
Oral
Dosage
- Heavy: ≥300 µg
- Light: 15–50 µg
- Common: 50–170 µg
- Strong: 170–300 µg
- Threshold: 15 µg
Duration
- Onset: 0.75-3 h
- Peak: 3-5 h
- Offset: 7-12 h
- After Effects: 12-36 h
- Total Duration: 9-12 h
Sublingual
Dosage
- Heavy: ≥300 µg
- Light: 15–50 µg
- Common: 50–170 µg
- Strong: 170–300 µg
- Threshold: 15 µg
Duration
- Onset: 0.75-3 h
- Peak: 3-5 h
- Offset: 7-12 h
- After Effects: 12-36 h
- Total Duration: 9-12 h
Harm Reduction
Check interactions before mixing substances, pay attention to dose spacing and hydration, and treat all dosage guidance as approximate rather than guaranteed safe.
Sources
Substance data is aggregated from the following public harm-reduction and reference sources.
Links
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