MDMA is a classical entactogen of the substituted amphetamine class, first developed in 1912 by the pharmaceutical company Merck. It remained largely obscure until the 1970s, when it gained recognition in underground psychotherapy circles before spreading into nightlife and rave culture. Now one of the most popular recreational drugs worldwide, it is known for producing strong feelings of empathy, emotional closeness, and stimulation. Tablets sold as "ecstasy" frequently contain adulterants or other substances entirely.
MDMA molecular structure diagram from the DrugsPRO substance library.
Also known as: E, X, Md, Xtc, Emma, Экстази, Molly, Mandy, Adam
Classification
Chemical: Amphetamine
Chemical: Phenethylamine
Psychoactive: Entactogen
Psychoactive: Psychedelic
Psychoactive: Stimulant
Tag: Common
Tag: Empathogen
Tag: Habit-Forming
Tag: MDxx
Tag: Substituted amphetamine
Effects
Spontaneous Tactile Sensations
Stimulation
Difficulty Urinating
Jaw Tension
Teeth Grinding
Nystagmus
Euphoria
Mindfulness
Time Distortion
Enhanced Pattern Recognition
Social Openness
Empathy Enhancement
Vibrating Vision
Dehydration
Hallucinations
Tracers
Internal Hallucination
External Hallucination
Routes of Administration
Oral
Dosage
Heavy: 175+ mg
Light: 35 – 75 mg
Common: 75 – 125 mg
Strong: 125 – 175 mg
Threshold: 35 mg
Duration
Onset: 0.33-1.17 h
Comeup: 0.5-1 h
Peak: 1.5-2.5 h
Offset: 1-1.5 h
After Effects: 12-48 h
Total Duration: 4-6 h
Insufflated
Dosage
Common: 70-120 mg
Heavy: 165+ mg
Light: 30-70 mg
Strong: 120-165 mg
Threshold: 5 mg
Duration
Onset: 0.03-0.25 h
Peak: 1-2.5 h
Offset: 2.5-5 h
After Effects: 12-36 h
Total Duration: 3-5 h
Rectal
Dosage
Common: 70-120 mg
Heavy: 165 mg
Light: 30-70 mg
Strong: 120-165 mg
Duration
No data available for this section yet.
Harm Reduction
Check interactions before mixing substances, pay attention to dose spacing and hydration, and treat all dosage guidance as approximate rather than guaranteed safe.
Sources
Substance data is aggregated from the following public harm-reduction and reference sources.
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MDMA - гид по веществам DrugsPRO
MDMA: MDMA is a classical entactogen of the substituted amphetamine class, first developed in 1912 by the pharmaceutical company Merck. It remained largely obscure until the 1970s, when it gained recognition in underground psychotherapy circles before spreading into nightlife and rave culture. Now o
