Library

Метадон

Methadone (sold under trade names such as Dolophine and Methadose) is a synthetic opioid analgesic used for the treatment of moderate to severe pain and for the treatment of opioid addiction. It is commonly used to treat and manage the symptoms of opioid addiction. The subjective effects are similar to those of other synthetic opioids such as fentanyl, however, most users note a significantly stronger euphoria. Like dextropropoxyphene, the use of methadone is associated with cardiac arrhythmia, however it is more common with dextropropoxyphene than it is with methadone.

Метадон molecular structure
Метадон molecular structure diagram from the DrugsPRO substance library.

Also known as: Mud, Dolls, Metho, Juice, Wafers, Dolophine, Methadose, Diskets, Metadol, Metadol-D, Physeptone, Adolan, Depridol, Heptadon, Heptanon, Ketalgin, Mephenon, Dl-methadone, Methadonum

Classification

  • Chemical: Medicine
  • Chemical: Opioid
  • Psychoactive: Depressant
  • Tag: Common
  • Tag: Diphenylheptane
  • Tag: Diphenylpropylamine
  • Tag: Habit-Forming

Effects

  • Pupil Constriction
  • Increased Perspiration
  • Temperature Regulation Suppression
  • Decreased Blood Pressure
  • Decreased Heart Rate
  • Pain Relief
  • Euphoria
  • Anxiety Suppression
  • Confusion
  • Memory Suppression
  • Thought Deceleration
  • Dizziness
  • Decreased Libido
  • Visual Acuity Suppression
  • Dulled Perception

Routes of Administration

Oral

Dosage

  • Heavy: 50+ mg
  • Light: 2 – 5 mg
  • Common: 5 – 15 mg
  • Strong: 15 – 30 mg
  • Threshold: 2–5 mg

Duration

  • Onset: 0.33-1.5 h
  • Comeup: 2-4 h
  • Peak: 4-6 h
  • Offset: 12-24 h
  • After Effects: 24-48 h
  • Total Duration: 8-24 h

Intravenous

Dosage

  • Heavy: 40+ mg
  • Light: 2–5 mg
  • Common: 5–20 mg
  • Strong: 20–40 mg
  • Threshold: 1–2 mg

Duration

  • Onset: 0-0.17 h
  • Peak: 0.17-0.5 h
  • Offset: 6-12 h
  • After Effects: 12-24 h
  • Total Duration: 6-12 h

Harm Reduction

Check interactions before mixing substances, pay attention to dose spacing and hydration, and treat all dosage guidance as approximate rather than guaranteed safe.

Sources

Substance data is aggregated from the following public harm-reduction and reference sources.

Links

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Methadone - гид по веществам DrugsPRO

Methadone: Methadone (sold under trade names such as Dolophine and Methadose) is a synthetic opioid analgesic used for the treatment of moderate to severe pain and for the treatment of opioid addiction. It is commonly used to treat and manage the symptoms of opioid addiction. The subjective effects

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