Bupropion is an atypical antidepressant belonging to the substituted cathinone and phenethylamine classes. First marketed under the brand name Wellbutrin, it functions as a norepinephrine-dopamine reuptake inhibitor (NDRI) and is prescribed for major depressive disorder, seasonal affective disorder, and smoking cessation. Unlike typical antidepressants, bupropion is less associated with sexual dysfunction and weight gain. It carries an elevated seizure risk, particularly in predisposed individuals, and should not be combined with other drugs without caution.
Bupropión molecular structure diagram from the DrugsPRO substance library.
Also known as: Buproprion, Zyban, Wellbutrin, Amfebutamone, Wellbutrin xl
Classification
Chemical: Cathinone
Chemical: Medicine
Chemical: Phenethylamine
Psychoactive: Depressant
Psychoactive: Nootropic
Psychoactive: Stimulant
Tag: Antidepressant
Tag: Habit-Forming
Tag: Pharmaceutical
Effects
Excessive Sweating
Increased Heart Rate
Increased Blood Pressure
Ataxia
Seizure
Sedation
Euphoria
Mood Lift
Anxiety
Irritability
Paranoia
Focus Enhancement
Appetite Suppression
Auditory Hallucination
External Hallucination
Light Sensitivity
Dulled Perception
Sexual Dysfunction
Routes of Administration
Oral
Dosage
No data available for this section yet.
Duration
Onset: 0.25-1.5 h
After Effects: 1-6 h
Harm Reduction
Check interactions before mixing substances, pay attention to dose spacing and hydration, and treat all dosage guidance as approximate rather than guaranteed safe.
Sources
Substance data is aggregated from the following public harm-reduction and reference sources.
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Bupropion - DrugsPRO sprievodca látky
Bupropion: Bupropion is an atypical antidepressant belonging to the substituted cathinone and phenethylamine classes. First marketed under the brand name Wellbutrin, it functions as a norepinephrine-dopamine reuptake inhibitor (NDRI) and is prescribed for major depressive disorder, seasonal affectiv