Caffeine is a naturally occurring stimulant of the methylxanthine class and the most widely consumed psychoactive substance in the world. Found in coffee beans, tea leaves, cacao, and numerous other plants, it is primarily used for its wakefulness-promoting, cognitive-enhancing, and physical performance-boosting properties. While it has a generally favorable safety profile, regular heavy use can produce physical dependence. Pure powder forms carry a greater risk of accidental overdose.
Kofeín molecular structure diagram from the DrugsPRO substance library.
Also known as: Čaj, Many, Theine, Káva, Mateine, Methyltheobromine, 7-methyltheophylline, Caffeinum, Coffein, Koffein, Cafeína, Caféine, Guaranine
Classification
Chemical: Medicine
Chemical: Xanthine
Psychoactive: Nootropic
Psychoactive: Stimulant
Tag: Common
Tag: Habit-Forming
Effects
Stimulation
Frequent Urination
Bronchodilation
Increased Heart Rate
Increased Blood Pressure
Elevated Heartrate
Wakefulness
Thought Acceleration
Analysis Enhancement
Focus Enhancement
Memory Enhancement
Motivation Enhancement
Appetite Suppression
Tactile Enhancement
Increased Libido
Auditory Enhancement
Brightness Enhancement
Taste Suppression
Routes of Administration
Oral
Dosage
Heavy: 400+ mg
Light: 10 – 75 mg
Common: 75-250 mg
Strong: 250 – 400 mg
Threshold: 10-20 mg
Duration
Onset: 0.08-0.75 h
Comeup: 0.2-1 h
Peak: 0.5-1.25 h
Offset: 6-10 h
After Effects: 6-24 h
Total Duration: 1.5-5 h
Insufflated
Dosage
Threshold: 2.5 mg
Heavy: 80 mg
Common: 25-40 mg
Light: 10-25 mg
Strong: 40-80 mg
Duration
Onset: 0 h
Comeup: 0 h
Peak: 0.5-1 h
Offset: 6-10 h
After Effects: 6-24 h
Smoked
Dosage
Threshold: 25 mg
Heavy: 175 mg
Common: 75-125 mg
Light: 25-75 mg
Strong: 125-175 mg
Duration
Onset: 0-0.1 h
Peak: 0.2-0.3 h
Offset: 0.5-0.8 h
After Effects: 2-4 h
Harm Reduction
Check interactions before mixing substances, pay attention to dose spacing and hydration, and treat all dosage guidance as approximate rather than guaranteed safe.
Sources
Substance data is aggregated from the following public harm-reduction and reference sources.
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Caffeine - DrugsPRO sprievodca látky
Caffeine: Caffeine is a naturally occurring stimulant of the methylxanthine class and the most widely consumed psychoactive substance in the world. Found in coffee beans, tea leaves, cacao, and numerous other plants, it is primarily used for its wakefulness-promoting, cognitive-enhancing, and physic
