Clozapine, sold under the brand name Clozaril among others, is a psychiatric medication and was the first atypical antipsychotic to be discovered. It is used primarily to treat people with schizophrenia and schizoaffective disorder who have had an inadequate response to two other antipsychotics, or who have been unable to tolerate other drugs due to extrapyramidal side effects. In the US, clozapine is also approved for use in people with recurrent suicidal behavior in people with schizophrenia or schizoaffective disorder. It is also used for the treatment of psychosis in Parkinson's disease.
Klozapín molecular structure diagram from the DrugsPRO substance library.
Also known as: Clozapine hydrochloride
Classification
Chemical: Medicine
Psychoactive: Depressant
Tag: Antipsychotic
Tag: Atypical antipsychotic
Tag: Pharmaceutical
Effects
Sedation
Motor Impairment
Itchiness
Respiratory Depression
Pupil Constriction
Analgesia
Reduced Anxiety
Anxiety Suppression
Dizziness
Euphoria
Cognitive Euphoria
Compulsive Redosing
Dulled Perception
Dehydration
Appetite Change
Entity Imagery
Open Eye Visuals
Voices
Routes of Administration
No route information available yet.
Harm Reduction
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Sources
Substance data is aggregated from the following public harm-reduction and reference sources.
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Clozapine - DrugsPRO sprievodca látky
Clozapine: Clozapine, sold under the brand name Clozaril among others, is a psychiatric medication and was the first atypical antipsychotic to be discovered. It is used primarily to treat people with schizophrenia and schizoaffective disorder who have had an inadequate response to two other antipsyc