GHB

GHB has an extremely steep dose-response curve; the difference between a recreational and dangerous dose can be as little as 1-2 grams. Doses above 10 grams are associated with high risk of death. Never combine with alcohol or other depressants. Always measure doses precisely using accurate equipment and wait at least 2-4 hours between doses. GHB is used medically as sodium oxybate (Xyrem) for narcolepsy treatment.

GHB molecular structure diagram from the DrugsPRO substance library.

Also known as: Gamma-hydroxybutyric acid, G, Gina, Xyrem, Fantasy, Liquid x, Liquid Ecstasy, Scoop, Γ-hydroxybutyrate

Classification

Chemical: GHB analogue
Chemical: Medicine
Psychoactive: Depressant
Tag: GABA analogue
Tag: GABAergic
Tag: gamma-Hydroxy acid
Tag: Habit-Forming
Tag: Sedative

Effects

Sedation
Muscle Relaxation
Nausea
Respiratory Depression
Sleepiness
Physical Comfort
Euphoria
Anxiety Suppression
Cognitive Euphoria
Empathy Enhancement
Sociability Enhancement
Motor Control Loss
Disinhibition
Increased Libido
Decreased Libido
Visual Haziness
Dulled Perception
Open Eye Visuals

Routes of Administration

Oral

Dosage

Threshold: 0.5 g
Light: 0.5–1.5 g
Common: 1-2.5 g
Strong: 2.5-3.5 g
Heavy: ≥4 g (often causes unrousable sleep)

Duration

Onset: 0.17-0.67 h
Comeup: 0.17-0.33 h
Peak: 0.75-1.5 h
Offset: 0.25-0.5 h
After Effects: 2-4 h
Total Duration: 1-3 h

Harm Reduction

Check interactions before mixing substances, pay attention to dose spacing and hydration, and treat all dosage guidance as approximate rather than guaranteed safe.

Sources

Substance data is aggregated from the following public harm-reduction and reference sources.

dose.wiki

Links

This static page is intended as a readable non-JS and prerender-friendly library export.

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GHB